SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022

被引：60

作者：

Sievers, Claudia ^{[1
,2
,3
]}

Zacher, Benedikt ^{[1
]}

Ullrich, Alexander ^{[1
]}

Huska, Matthew ^{[4
]}

Fuchs, Stephan ^{[4
]}

Buda, Silke ^{[1
]}

Haas, Walter ^{[1
]}

Diercke, Michaela ^{[1
]}

an der Heiden, Matthias ^{[1
]}

Kroeger, Stefan ^{[1
]}

机构：

[1] Robert Koch Inst, Dept Infect Dis Epidemiol, Berlin, Germany

[2] Robert Koch Inst, Postgrad Training Appl Epidemiol PAE, Berlin, Germany

[3] European Ctr Dis Prevent & Control ECDC, European Programme Intervent Epidemiol Training E, Stockholm, Sweden

[4] Robert Koch Inst, Dept Genome Sequencing & Genom Epidemiol, Berlin, Germany

来源：

EUROSURVEILLANCE | 2022年 / 27卷 / 22期

关键词：

D O I：

10.2807/1560-7917.ES.2022.27.22.2200396

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in = 35-year- olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.

引用

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