68Ga-DOTATATE Significance of Uptake in the Tail of the Pancreas in Patients Without Lesions

被引:3
作者
Delbeke, Dominique [1 ]
Newman, Grace [1 ]
Deppen, Steve [2 ,3 ,4 ]
Shah, Chirayu [2 ,5 ]
Ndolo, Josephine [1 ]
Shi, Chanjuan [6 ]
Bailey, Christina E. [7 ]
Jessop, Aaron C. [1 ]
Sandler, Martin P. [1 ]
机构
[1] Vanderbilt Univ, Dept Radiol & Radiol Sci, Div Nucl Med, Med Ctr, Nashville, TN 37232 USA
[2] Tennessee Valley Healthcare Syst, Vet Affairs Hosp, Nashville, TN USA
[3] Vanderbilt Univ, Dept Thorac Surg, Med Ctr, Nashville, TN 37232 USA
[4] Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA
[5] Vanderbilt Univ, Med Ctr, Dept Radiol, Nashville, TN 37232 USA
[6] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN 37232 USA
[7] Vanderbilt Univ, Med Ctr, Div Surg Oncol & Endocrine Surg, Dept Surg, Nashville, TN 37232 USA
关键词
neuroendocrine; pancreas; DOTATATE; PET; SOMATOSTATIN RECEPTOR SCINTIGRAPHY; PET/CT; GUIDELINES; DIAGNOSIS; DOSIMETRY; TUMORS;
D O I
10.1097/RLU.0000000000002757
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose To measure the SUVs in the tail of the pancreas compared with normal liver parenchyma and somatostatin receptor-positive lesions. Materials and Methods Ga-68-DOTATATE PET/low mAs CT of 35 patients were reviewed. Results There was no significant difference (P = 0.59) between the SUVaverage of normal liver and the SUVpeak of normal tail. Five patients had uptake in the tail slightly above that of normal liver that were interpreted equivocally. In one of these patients with Ga-68-DOTATATE uptake in a peripancreatic lymph node, proven neuroendocrine tumor underwent a distal pancreatectomy and pathologic examination revealed islet cell hyperplasia. Conclusions Ga-68-DOTATATE uptake in the tail of the pancreas above that of normal liver indicates a somatostatin receptor-avid lesion. Uptake in the tail of the pancreas equal to the liver can be normal. Patients with uptake equivalent to the liver should undergo further anatomical imaging before procedural intervention.
引用
收藏
页码:851 / 854
页数:4
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