Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy

被引：40

作者：

Greinacher, Andreas ^{[1
]}

Langer, Florian ^{[2
]}

Schoenborn, Linda ^{[1
]}

Thiele, Thomas ^{[1
]}

Haddad, Munif ^{[3
]}

Renne, Thomas ^{[3
,4
,5
]}

Rollin, Jerome ^{[6
,7
]}

Gruel, Yves ^{[6
,7
]}

Warkentin, Theodore E. ^{[8
,9
]}

机构：

[1] Univ Med Greifswald, Inst Immunol & Transfus Med, Abt Transfus Med, Greifswald, Germany

[2] Univ Klinikum Eppendorf, Zentrum Onkol 2, Med Klin & Poliklin, Hamburg, Germany

[3] Univ Med Ctr Hamburg Eppendorf, Inst Clin Chem & Lab Med, Hamburg, Germany

[4] Johannes Gutenberg Univ Mainz, Ctr Thrombosis & Hemostasis CTH, Med Ctr, Mainz, Germany

[5] Royal Coll Surgeons Ireland, Irish Ctr Vasc Biol, Sch Pharm & Biomol Sci, Dublin, Ireland

[6] Reg Univ Hosp Ctr Tours, Dept Hemostasis, Tours, France

[7] Univ Tours, EA7501 GICC, Tours, France

[8] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

[9] McMaster Univ, Dept Med, Hamilton, ON, Canada

来源：

HAEMATOLOGICA | 2022年 / 107卷 / 05期

关键词：

D O I：

10.3324/haematol.2021.280366

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1219 / 1221

页数：3

共 5 条

[1]

Faille DH-NMO A., 2017, RES PRACT THROMB HAE, V1, P1355

[2] Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination [J].

Greinacher, Andreas ;

Thiele, Thomas ;

Warkentin, Theodore E. ;

Weisser, Karin ;

Kyrle, Paul A. ;

Eichinger, Sabine .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (22) :2092-2101

[3]

Greinacher Andreas, 2021, Blood, V138, P1269, DOI 10.1182/blood.2021012938

[4] Characterization of New Monoclonal PF4-Specific Antibodies as Useful Tools for Studies on Typical and Autoimmune Heparin-Induced Thrombocytopenia [J].

Vayne, Caroline ;

Nguyen, Thi-Huong ;

Rollin, Jerome ;

Charuel, Noemie ;

Poupon, Anne ;

Pouplard, Claire ;

Normann, Nicole ;

Gruel, Yves ;

Greinacher, Andreas .

THROMBOSIS AND HAEMOSTASIS, 2021, 121 (03) :322-331

[5] Spontaneous HIT syndrome: Knee replacement, infection, and parallels with vaccine-induced immune thrombotic thrombocytopenia [J].

Warkentin, Theodore E. ;

Greinacher, Andreas .

THROMBOSIS RESEARCH, 2021, 204 :40-51

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