Cadmium activates Arabidopsis MPK3 and MPK6 via accumulation of reactive oxygen species

被引：124

作者：

Liu, Xiao-Min ^{[1
]}

Kim, Kyung Eun ^{[1
]}

Kim, Kang-Chang ^{[1
]}

Nguyen, Xuan Canh ^{[1
]}

Han, Hay Ju ^{[1
]}

Jung, Mi Soon ^{[1
]}

Kim, Ho Soo ^{[1
,2
]}

Kim, Sun Ho ^{[2
]}

Park, Hyeong Cheol ^{[1
,2
]}

Yun, Dae-Jin ^{[1
,2
]}

Chung, Woo Sik ^{[1
,2
]}

机构：

[1] Gyeongsang Natl Univ, Div Appl Life Sci, Program BK21, Plant Mol Biol & Biotechnol Res Ctr, Jinju 660701, South Korea

[2] Gyeongsang Natl Univ, Environm Biotechnol Natl Core Res Ctr, Jinju 660701, South Korea

来源：

PHYTOCHEMISTRY | 2010年 / 71卷 / 5-6期

关键词：

Arabidopsis; Cruciferae; Cadmium; Heavy metal; MAPK; Reactive oxygen species; Signal transduction; PROTEIN-KINASE GENE; HEAVY-METAL STRESS; MAP KINASE; THALIANA; MAIZE; TRANSPORTER; RESPONSES;

D O I：

10.1016/j.phytochem.2010.01.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cadmium (Cd) is a non-essential toxic heavy metal that influences normal growth and development of plants. However, the molecular mechanisms by which plants recognize and respond to Cd remain poorly understood. We show that, in Arabidopsis. Cd activates the mitogen-activated protein kinases, MPK3 and MPK6, in a dose-dependent manner. Following treatment with Cd, these two MAPKs exhibited much higher activity in the roots than in the leaves, and pre-treatment with the reactive oxygen species (ROS) scavenger, glutathione, effectively inhibited their activation. These results suggest that the Cd sensing signaling pathway uses a build-up of ROS to trigger activation of Arabidopsis MPK3 and MPK6. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：614 / 618

页数：5

共 34 条

[1] Stress hormone-independent activation and nuclear translocation of mitogen-activated protein kinases in Arabidopsis thaliana during ozone exposure [J].