Endometrial receptivity in eutopic endometrium in patients with endometriosis: it is not affected, and let me show you why

被引:56
作者
Miravet-Valenciano, Jose [1 ]
Ruiz-Alonso, Maria [1 ]
Gomez, Eva [1 ]
Garcia-Velasco, Juan A. [2 ]
机构
[1] IGenomix, Valencia, Spain
[2] Rey Juan Carlos Univ, IdiPAZ, IVI Madrid, Madrid, Spain
关键词
Endometrial receptivity; transcriptomic signature; array; IN-VITRO FERTILIZATION; GENE-EXPRESSION; INVITRO FERTILIZATION; IMPLANTATION WINDOW; OOCYTE DONATION; WOMEN; BIOMARKERS; INFERTILITY; RECIPIENTS; PROGRAM;
D O I
10.1016/j.fertnstert.2017.06.002
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Many women with endometriosis experience compromised fertility. This disease clearly exerts quantitative damage on the ovaries, and perhaps, also qualitative damage. However, it remains controversial whether endometrial receptivity is compromised. Here we review the evidence from basic transcriptomic signature data to clinical data from an oocyte donation model and find support for the concept that endometrial receptivity is not impaired in women with endometriosis when healthy embryos reach the endometrial cavity. (C) 2017 by American Society for Reproductive Medicine.
引用
收藏
页码:28 / 31
页数:4
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