Chronic Q-Fever (Coxiella burnetii) Causing Abdominal Aortic Aneurysm and Lumbar Osteomyelitis: A Case Report

被引：8

作者：

Leahey, P. Alexander ^{[1
]}

Tahan, Steven R. ^{[2
]}

Kasper, Ekkehard M. ^{[3
]}

Albrecht, Mary ^{[1
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Div Infect Dis, Boston, MA 02215 USA

[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Div Pathol, Boston, MA 02215 USA

[3] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Div Neurosurg, Boston, MA 02215 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2016年 / 3卷 / 01期

关键词：

abdominal aortic aneurysm; chronic Q-fever; Coxiella burnetii; osteomyelitis; Q-fever; INFECTION;

D O I：

10.1093/ofid/ofv185

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Coxiella burnetii is a rare cause of chronic infection that most frequently presents as endocarditis. We report a case of C burnetii causing an infected abdominal aortic aneurysm with contiguous lumbar osteomyelitis resulting in spinal cord compromise. The diagnosis was established by serologic studies consistent with chronic Q-fever (ratio of C burnetii immunoglobulin [Ig]G phase II titer to IgG phase I titer <1) and was confirmed by positive C burnetii polymerase chain reaction of vertebral tissue in addition to pathology of vertebral bone showing intracellular Gram-negative coccobacillary bacteria. The patient clinically improved after surgical decompression and prolonged treatment with doxycycline and hydroxychloroquine.

引用

页数：3

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