Two New Xanthones from Comastoma pulmonarium and Their Anti-Tobacco Mosaic Virus Activity

被引：1

作者：

Hu, Qiu-Fen ^{[1
]}

Wang, Xiao-Long ^{[1
,2
]}

Zeng, Wan-Li ^{[2
]}

Wang, Jin ^{[2
]}

Xu, Yong ^{[2
]}

Huang, Hai-Tao ^{[2
]}

Li, Jing ^{[2
]}

Liu, Xin ^{[2
]}

Yang, Guang-Yu ^{[2
]}

Li, Xue-Mei ^{[2
]}

Zhang, Cheng-Ming ^{[2
]}

Li, Gang-Peng ^{[1
,2
]}

机构：

[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Yunnan, Peoples R China

[2] China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Yunnan, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2019年 / 55卷 / 06期

基金：

中国国家自然科学基金;

关键词：

xanthones; Comastoma pulmonarium; anti-tobacco mosaic virus activity; STEMS;

D O I：

10.1007/s10600-019-02888-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new xanthones (1 and 2), together with three known xanthones (3-5), were isolated from the whole plants of Comastoma pulmonarium. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 42.8% and 52.4%, respectively. These rates are higher than that of positive control.

引用

页码：1039 / 1042

页数：4

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