AKT and the phosphatidylinositol 3-kinase/AKT pathway: Important molecular targets for lung cancer prevention and treatment

被引：25

作者：

Crowell, JA ^{[1
]}

Steele, VE ^{[1
]}

机构：

[1] NCI, Chemoprevent Agent Dev Res Grp, EPN,Div Canc Preven, NIH,Dept Hlth & Human Serv, Bethesda, MD 20892 USA

来源：

JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2003年 / 95卷 / 04期

关键词：

DEGUELIN;

D O I：

10.1093/jnci/95.4.252

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：252 / 253

页数：2

共 8 条

[1]

CHUN KH, 2003, J NATL CANC I, V95

[2] Anticancer action of cube insecticide:: Correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities [J].

Fang, NB ;

Casida, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (07) :3380-3384

[3]

KLAASSEN CD, 2001, CASARETT DOULLS TOXI, P609

[4] Discovery of cancer preventive agents from natural products: from plants to prevention. [J].

Mehta R.G. ;

Pezzuto J.M. .

Current Oncology Reports, 2002, 4 (6) :478-486

[5]

Udeani GO, 1997, CANCER RES, V57, P3424

[6] Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats [J].

Udeani, GO ;

Zhao, GM ;

Shin, YG ;

Kosmeder, JW ;

Beecher, CWW ;

Kinghorn, AD ;

Moriarty, RM ;

Moon, RC ;

Pezzuto, JM .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2001, 47 (03) :263-268

[7] The phosphatidylinositol 3-kinase-AKT pathway in human cancer [J].

Vivanco, I ;

Sawyers, CL .

NATURE REVIEWS CANCER, 2002, 2 (07) :489-501

[8] Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells [J].

West, KA ;

Brognard, J ;

Clark, AS ;

Linnoila, IR ;

Yang, XW ;

Swain, SM ;

Harris, C ;

Belinsky, S ;

Dennis, PA .

JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (01) :81-90

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