A photoCORM nanocarrier for CO release using NIR light

被引：107
作者：
Pierri, Agustin E. [1 ,2 ,3 ]
Huang, Po-Ju [1 ]
Garcia, John V. [1 ]
Stanfill, James G. [1 ]
Chui, Megan [1 ]
Wu, Guang [1 ]
Zheng, Nanfeng [2 ,3 ]
Ford, Peter C. [1 ]
机构：
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
[2] Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China
[3] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 11期
基金：
美国国家科学基金会;
关键词：
NITRIC-OXIDE RELEASE; CARBON-MONOXIDE; NITROSYL COMPLEX; VISIBLE-LIGHT; THERAPY; NANOPARTICLES; EXCITATION; DELIVERY;
D O I：
10.1039/c4cc06766e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A water-soluble nanocarrier for a photo-activated CO releasing moiety (photoCORM) that can be triggered with NIR excitation is described. This has an upconversion nanoparticle core encapsulated by an amphiphilic polymer imparting both water solubility and a hydrophobic interior containing the photoCORM trans-Mn(bpy)(PPh3)(2)(CO)(2). Such an ensemble offers a unique strategy for CO delivery to biological targets.
引用
收藏
页码：2072 / 2075
页数：4
相关论文
共 40 条
[1]   Hard Proof of the NaYF4/NaGdF4 Nanocrystal Core/Shell Structure [J].
Abel, Keith A. ;
Boyer, John-Christopher ;
van Veggel, Frank C. J. M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (41) :14644-+
[2]   Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes [J].
Atkin, Anthony J. ;
Lynam, Jason M. ;
Moulton, Benjamin E. ;
Sawle, Philip ;
Motterlini, Roberto ;
Boyle, Nicola M. ;
Pryce, Mary T. ;
Fairlamb, Ian J. S. .
DALTON TRANSACTIONS, 2011, 40 (21) :5755-5761
[3]   Nitric Oxide Releasing Materials Triggered by Near-Infrared Excitation Through Tissue Filters [J].
Burks, Peter T. ;
Garcia, John V. ;
GonzalezIrias, Ricardo ;
Tillman, Jason T. ;
Niu, Mutong ;
Mikhailovsky, Alexander A. ;
Zhang, Jinping ;
Zhang, Fan ;
Ford, Peter C. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (48) :18145-18152
[4]   Remote-Control Photorelease of Caged Compounds Using Near-Infrared Light and Upconverting Nanoparticles [J].
Carling, Carl-Johan ;
Nourmohammadian, Farahnaz ;
Boyer, John-Christopher ;
Branda, Neil R. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (22) :3782-3785
[5]   Rapid CO release from a Mn(I) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells [J].
Carrington, Samantha J. ;
Chakraborty, Indranil ;
Mascharak, Pradip K. .
CHEMICAL COMMUNICATIONS, 2013, 49 (96) :11254-11256
[6]   Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets [J].
Chakraborty, Indranil ;
Carrington, Samantha J. ;
Mascharak, Pradip K. .
ACCOUNTS OF CHEMICAL RESEARCH, 2014, 47 (08) :2603-2611
[7]   Orthorhombic KSc2F7:Yb/Er nanorods: controlled synthesis and strong red upconversion emission [J].
Ding, Yujie ;
Teng, Xue ;
Zhu, Hao ;
Wang, Lili ;
Pei, Wenbo ;
Zhu, Jun-Jie ;
Huang, Ling ;
Huang, Wei .
NANOSCALE, 2013, 5 (23) :11928-11932
[8]   MECHANISTIC ASPECTS OF THE PHOTOSUBSTITUTION AND PHOTO-ISOMERIZATION REACTIONS OF D6-METAL COMPLEXES [J].
FORD, PC ;
WINK, D ;
DIBENEDETTO, J .
PROGRESS IN INORGANIC CHEMISTRY, 1983, 30 :213-271
[9]   Multi-photon excitation in uncaging the small molecule bioregulator nitric oxide [J].
Garcia, John V. ;
Zhang, Fan ;
Ford, Peter C. .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2013, 371 (1995)
[10]   NIR-Triggered Release of Caged Nitric Oxide using Upconverting Nanostructured Materials [J].
Garcia, John V. ;
Yang, Jianping ;
Shen, Dengke ;
Yao, Chi ;
Li, Xiaoming ;
Wang, Rui ;
Stucky, Galen D. ;
Zhao, Dongyuan ;
Ford, Peter C. ;
Zhang, Fan .
SMALL, 2012, 8 (24) :3800-3805
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