Kidney transplant practice patterns and outcome benchmarks over 30 years: The 2018 report of the NAPRTCS

被引:100
作者
Chua, Annabelle [1 ,10 ]
Cramer, Carl [2 ,48 ]
Moudgil, Asha [3 ,55 ]
Martz, Karen [4 ]
Smith, Jodi [5 ]
Blydt-Hansen, Tom [6 ,30 ]
Neu, Alicia [7 ]
Dharnidharka, Vikas R. [8 ]
Somers, Michael [9 ]
Chua, Annabelle [1 ,10 ]
Barcia, John [11 ]
Hooper, David [12 ]
Barletta, Gina-Marie [13 ]
Turman, Martin
Restaino, Irene [14 ]
Garimella, Sudha [15 ]
Belsha, Craig [16 ]
Lo, Megan [17 ]
Harvey, Elizabeth [18 ]
Salusky, Isidro [19 ]
Yadin, Ora [19 ]
Lee, Marsha [20 ]
Langman, Craig [21 ]
Atkinson, Meredith [22 ]
Greenbaum, Laurence [23 ]
Warady, Bradley [24 ]
Bartosh, Sharon [25 ]
Seikaly, Mouin [26 ]
Mongia, Anil [27 ]
Swinford, Rita [28 ]
Onder, Ali Mirza [29 ]
Blydt-Hansen, Tom [6 ,30 ]
Lovell, Helen [31 ]
Rheault, Michelle [32 ]
Kumar, Juhi [33 ]
Lee-Son, Kathy [34 ]
Hesemann, Laura [35 ]
Benador, Nadine [36 ]
Arar, Mazen [37 ]
Abitbol, Carolyn
Luckritz, Kera [38 ]
Benchimol, Corinne [39 ]
Fathallah-Shaykh, Sahar [40 ]
Flynn, Joseph [41 ]
Raina, Rupesh [42 ]
Dixit, Mehul [43 ]
Pan, Cynthia [44 ]
Patel, Hiren [45 ]
Kapur, Gaurav [46 ]
Czech, Kimberly [47 ]
机构
[1] Duke Univ, Div Pediat Nephrol, Durham, NC USA
[2] Mayo Clin, Div Pediat Nephrol, Rochester, MN USA
[3] Childrens Natl Med Ctr, Div Pediat Nephrol, Washington, DC 20010 USA
[4] Emmes Corp, Rockville, MD USA
[5] Univ Washington, Seattle Childrens Hosp, Div Pediat Nephrol, Seattle, WA 98195 USA
[6] BC Childrens Hosp, Div Pediat Nephrol, Vancouver, BC, Canada
[7] Johns Hopkins Univ, Div Pediat Nephrol, Baltimore, MD USA
[8] Washington Univ, St Louis Childrens Hosp, Sch Med, Div Pediat Nephrol Hypertens & Pheresis, St Louis, MO 63110 USA
[9] Boston Childrens Hosp, Boston, MA USA
[10] Duke Univ, Durham, NC USA
[11] Univ Virginia, Charlottesville, VA 22903 USA
[12] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
[13] Phoenix Childrens Hosp, Phoenix, AZ USA
[14] Childrens Hosp Kings Daughters, Norfolk, VA USA
[15] SUNY Buffalo, Buffalo, NY USA
[16] Cardinal Glennon Childrens Hosp, St Louis, MO USA
[17] Virginia Commonwealth Univ, Richmond, VA 23284 USA
[18] Hosp Sick Children, Toronto, ON, Canada
[19] Univ Calif Los Angeles, Los Angeles, CA 90024 USA
[20] Univ Calif San Francisco, San Francisco, CA 94143 USA
[21] Lurie Childrens Hosp, Chicago, IL USA
[22] Johns Hopkins Univ, Baltimore, MD 21218 USA
[23] Emory Univ, Atlanta, GA 30322 USA
[24] Childrens Mercy Kansas City, Kansas City, MO USA
[25] Univ Wisconsin, Madison, WI 53706 USA
[26] Childrens Med Ctr, Dallas, TX 75235 USA
[27] SUNY Brooklyn, Brooklyn, NY USA
[28] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA
[29] LeBonheur Childrens Hosp, Memphis, TN USA
[30] Childrens Hosp British Columbia, Vancouver, BC, Canada
[31] Univ Nebraska, Lincoln, NE 68583 USA
[32] Univ Minnesota, Minneapolis, MN 55455 USA
[33] Cornell Univ, Ithaca, NY 14853 USA
[34] Univ Iowa, Iowa City, IA 52242 USA
[35] Univ Missouri, Columbia, MO 65211 USA
[36] Univ Calif San Diego, La Jolla, CA 92093 USA
[37] Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX 78229 USA
[38] Univ Miami, Coral Gables, FL 33124 USA
[39] Mt Sinai, New York, NY USA
[40] Univ Alabama Birmingham, Birmingham, AL USA
[41] Seattle Childrens Hosp, Seattle, WA USA
[42] Childrens Hosp, Med Ctr Akron, Akron, OH 44308 USA
[43] Univ Mississippi, University, MS 38677 USA
[44] Childrens Hosp Wisconsin, Milwaukee, WI 53201 USA
[45] Nationwide Childrens Hosp, Columbus, OH USA
[46] Childrens Hosp Michigan, Detroit, MI 48201 USA
[47] Univ Illinois, Chicago, IL 60680 USA
[48] Mayo Clin, Rochester, MN USA
[49] Massachusetts Gen Hosp, Boston, MA 02114 USA
[50] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA
关键词
acute rejection; graft survival; infections; kidney; malignancies; pediatric; transplantation; PEDIATRIC RENAL-TRANSPLANTATION; ALLOGRAFT SURVIVAL; RANDOMIZED-TRIAL; GRAFT FAILURE; CHILDREN; AGE; CYCLOSPORINE; BASILIXIMAB; TACROLIMUS; RECIPIENTS;
D O I
10.1111/petr.13597
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The NAPRTCS has collected clinical information on children undergoing renal transplantation since 1987 and now includes information on 12 920 renal transplants in 11 870 patients. Since the first data analysis in 1989, NAPRTCS reports have documented marked improvements in patient and allograft outcomes after pediatric renal transplantation in addition to identifying factors associated with both favorable and poor outcomes. The registry has served to document and influence practice patterns, clinical outcomes, and changing trends in renal transplantation and also provides historical perspective. This report highlights current practices in an era of major changes in DD kidney allocation and continuing steroid minimization. This report presents outcomes of the patients in the NAPRTCS transplant registry up to end of 2017. In particular, an increase in the cumulative incidence of late first AR has occurred in the most recent cohort, while all prior cohorts had a lower cumulative incidence of late first AR.
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页数:17
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