Carcinoid Heart Disease A Guide for Clinicians

被引：9
作者：
Perry, Daniel [1 ]
Hayek, Salim S. [1 ]
机构：
[1] Univ Michigan, Dept Med, Div Cardiol, 1500 East Med Ctr Dr, Ann Arbor, MI 48109 USA
来源：
CARDIOLOGY CLINICS | 2019年 / 37卷 / 04期
关键词：
Carcinoid syndrome; HIAA; Tricuspid valve; Pulmonic valve; Regurgitation; Right heart failure; BRAIN NATRIURETIC PEPTIDE; IN-VALVE IMPLANTATION; TRANSCATHETER PULMONARY; NEUROENDOCRINE TUMORS; TELOTRISTAT ETIPRATE; PROGRESSION; SURGERY;
D O I：
10.1016/j.ccl.2019.07.014
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Carcinoid heart disease is the collective term for all cardiac manifestations that develop in patients with carcinoid. The cardiac manifestations of carcinoid tumors are attributed to the paraneoplastic effects of vasoactive substances released by the malignant cells. The clinical manifestations of carcinoid heart disease include valvular destruction leading to valvular regurgitation and stenosis, right-sided heart failure, and metastatic carcinoid disease. A combination of biomarkers and cardiac imaging is used in screening and diagnosis of carcinoid heart disease in patients with carcinoid syndrome. The management of carcinoid heart disease involves medical and surgical treatment and requires a multidisciplinary approach for optimized care.
引用
收藏
页码：497 / +
页数：8
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