The impact of socioeconomic status on access to cancer clinical trials

被引：113

作者：

Sharrocks, K. ^{[1
]}

Spicer, J. ^{[2
]}

Camidge, D. R. ^{[3
]}

Papa, S. ^{[2
]}

机构：

[1] Guys & St Thomas NHS Fdn Trust, Dept Med Oncol, London SE1 9RT, England

[2] Guys Hosp, Kings Coll London, Dept Med, London SE1 9RT, England

[3] Univ Colorado, Ctr Canc, Developmental Therapeut Program, Aurora, CO 80045 USA

来源：

BRITISH JOURNAL OF CANCER | 2014年 / 111卷 / 09期

基金：

英国医学研究理事会;

关键词：

cancer clinical trials; socioeconomics; PARTICIPATION; EDUCATION; MORTALITY; BARRIERS; DISPARITIES; SURVIVAL; LEVEL; WOMEN;

D O I：

10.1038/bjc.2014.108

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cancer clinical trials enable the development of novel agents for the potential benefit of cancer patients. Enrolment in a trial offers patients the chance of superior efficacy coupled to the risk of unanticipated toxicity. For trial results to be generalisable, the data need to be collected in patients' representative of the general cancer population. Socioeconomic deprivation is associated with poor cancer outcomes. In the developed world, the gap between the most and least deprived is widening. This mini-review explores the evidence regarding socioeconomics and access to cancer trials, highlighting the underrepresentation of deprived patients, and exploring reasons for this disparity.

引用

页码：1684 / 1687

页数：4

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