Patent foramen ovale closure for secondary stroke prevention

被引：40
作者：
Alkhouli, Mohamad [1 ]
Sievert, Horst [2 ,3 ,4 ,5 ]
Holmes, David R. [6 ]
机构：
[1] West Virginia Univ, Sch Med, Div Cardiol, 1 Med Ctr Dr, Morgantown, WV 26505 USA
[2] CardioVasc Ctr Frankfurt, Dept Med, Seckbacher Landstr 65, D-60389 Frankfurt, Germany
[3] Anglia Ruskin Univ, Cambridge Campus,East Rd, Cambridge CB1 1PT, England
[4] Yunnan Hosp Fuwai, Intersect Shahe Beilu & Jinchuan Lu, Kunming, Yunnan, Peoples R China
[5] Univ Calif San Francisco, 550 16th St, San Francisco, CA 94158 USA
[6] Mayo Clin, Sch Med, Dept Cardiol, 200 1st St SW, Rochester, MN 55905 USA
来源：
EUROPEAN HEART JOURNAL | 2019年 / 40卷 / 28期
关键词：
Cryptogenic stroke; Patent foramen ovale; Device closure; Stroke prevention; ATRIAL SEPTAL-DEFECT; TO-LEFT SHUNT; TRANSCATHETER CLOSURE; MEDICAL THERAPY; PERCUTANEOUS CLOSURE; TRANSCRANIAL DOPPLER; CRYPTOGENIC STROKE; ISCHEMIC-STROKE; DEVICE; METAANALYSIS;
D O I：
10.1093/eurheartj/ehz157
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Transcatheter closure of patent foramen ovale (PFO) in patients with cryptogenic stroke is gaining momentum after the recent publication of four randomized clinical trials suggesting its benefit. This article provides a contemporary overview of the anatomy and pathophysiology of PFO, the available diagnostic tools for the assessment and risk stratification of PFO, and the current and future landscape of PFO closure devices and their optimal utilization. It also summarizes the current data on PFO closure for stroke prevention, and discusses the remaining open issues in the field of PFO closure.
引用
收藏
页码：2339 / +
页数：12
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