Clostridium difficile-associated diarrhea in a pediatric hospital

被引：10

作者：

Spivack, JG

Eppes, SC

Klein, JD

机构：

[1] Alfred I DuPont Hosp Children, Div Infect Dis, Nemours Childrens Clin Wilmington, Wilmington, DE 19899 USA

[2] Thomas Jefferson Univ, Jefferson Med Coll, Philadelphia, PA 19107 USA

来源：

CLINICAL PEDIATRICS | 2003年 / 42卷 / 04期

关键词：

PRACTICE GUIDELINES; COLITIS; COLONIZATION; POPULATION; MANAGEMENT; INFECTION; DIAGNOSIS; CHILDREN; TOXIN;

D O I：

10.1177/000992280304200407

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This retrospective cohort analysis examined the risk factors, symptoms, and severity of disease associated with C. difficile in pediatric inpatients. Risk factors for a C. difficile-positive test were an oncologic diagnosis, diarrhea of more than 2 days' duration, and gastrointestinal symptoms, especially abdominal pain. Over a 3.5-year period, there was a total of 22 C. difficile-positive patients, and most had mild, self-limiting diarrheal illness. No cases of C. difficile diarrhea were identified. Seventy-eight percent of the C. difficile-positive patients were found to have alternate risk factors for diarrhea. Our data indicate that C. difficile rarely causes severe diarrhea in pediatric inpatients and that C. difficile-positive testing should be limited to patients with severe prolonged diarrhea and abdominal pain.

引用

收藏

页码：347 / 352

页数：6

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