Herpes Simplex Virus Infection During Pregnancy

被引:29
作者
Stephenson-Famy, Alyssa [1 ]
Gardella, Carolyn [2 ,3 ]
机构
[1] Univ Washington, Dept Obstet & Gynecol, Div Maternal Fetal Med, Seattle, WA 98195 USA
[2] Univ Washington, Dept Obstet & Gynecol, Div Womens Hlth, Seattle, WA 98195 USA
[3] VA Puget Sound Med Ctr, Dept Gynecol, Seattle, WA 98108 USA
关键词
Genital herpes; Pregnancy; Antiviral therapy; Prevention; Neonatal herpes; Serologic screening; RECURRENT GENITAL HERPES; PLACEBO-CONTROLLED TRIAL; NEONATAL HERPES; COST-EFFECTIVENESS; ACYCLOVIR PROPHYLAXIS; NATURAL-HISTORY; CESAREAN DELIVERY; UNITED-STATES; RISK-FACTORS; WOMEN;
D O I
10.1016/j.ogc.2014.08.006
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Genital herpes in pregnancy continues to cause significant maternal morbidity, with an increasing number of infections being due to orallabial transmission of herpes simplex virus (HSV)-1. Near delivery, primary infections with HSV-1 or HSV-2 carry the highest risk of neonatal herpes infection, which is a rare but potentially devastating disease for otherwise healthy newborns. Prevention efforts have been limited by lack of an effective intervention for preventing primary infections and the unclear role of routine serologic testing.
引用
收藏
页码:601 / +
页数:15
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