Herpes Simplex Virus Infection During Pregnancy

被引:29
作者
Stephenson-Famy, Alyssa [1 ]
Gardella, Carolyn [2 ,3 ]
机构
[1] Univ Washington, Dept Obstet & Gynecol, Div Maternal Fetal Med, Seattle, WA 98195 USA
[2] Univ Washington, Dept Obstet & Gynecol, Div Womens Hlth, Seattle, WA 98195 USA
[3] VA Puget Sound Med Ctr, Dept Gynecol, Seattle, WA 98108 USA
关键词
Genital herpes; Pregnancy; Antiviral therapy; Prevention; Neonatal herpes; Serologic screening; RECURRENT GENITAL HERPES; PLACEBO-CONTROLLED TRIAL; NEONATAL HERPES; COST-EFFECTIVENESS; ACYCLOVIR PROPHYLAXIS; NATURAL-HISTORY; CESAREAN DELIVERY; UNITED-STATES; RISK-FACTORS; WOMEN;
D O I
10.1016/j.ogc.2014.08.006
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Genital herpes in pregnancy continues to cause significant maternal morbidity, with an increasing number of infections being due to orallabial transmission of herpes simplex virus (HSV)-1. Near delivery, primary infections with HSV-1 or HSV-2 carry the highest risk of neonatal herpes infection, which is a rare but potentially devastating disease for otherwise healthy newborns. Prevention efforts have been limited by lack of an effective intervention for preventing primary infections and the unclear role of routine serologic testing.
引用
收藏
页码:601 / +
页数:15
相关论文
共 69 条
[1]  
ACOG Committee on Practice Bulletins, 2007, Obstet Gynecol, V109, P1489
[2]   Valacyclovir therapy to reduce recurrent genital herpes in pregnant women [J].
Andrews, WW ;
Kimberlin, DF ;
Whitley, R ;
Cliver, S ;
Ramsey, PS ;
Deeter, R .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2006, 194 (03) :774-781
[3]  
Baker D, 2004, NATION, V278, P2
[4]   Risk factors for herpes simplex virus transmission to pregnant women: A couples study [J].
Baker, DA .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 193 (06) :1887-1888
[5]  
Barnabas RV, 2012, CURR HIV RES, V10, P228, DOI 10.2174/157016212800618156
[6]   The potential role of suppressive therapy for sex partners in the prevention of neonatal herpes: a health economic analysis [J].
Barnabas, RV ;
Carabin, H ;
Garnett, GP .
SEXUALLY TRANSMITTED INFECTIONS, 2002, 78 (06) :425-429
[7]   Efficacy Results of a Trial of a Herpes Simplex Vaccine [J].
Belshe, Robert B. ;
Leone, Peter A. ;
Bernstein, David I. ;
Wald, Anna ;
Levin, Myron J. ;
Stapleton, Jack T. ;
Gorfinkel, Iris ;
Morrow, Rhoda L. Ashley ;
Ewell, Marian G. ;
Stokes-Riner, Abbie ;
Dubin, Gary ;
Heineman, Thomas C. ;
Schulte, Joann M. ;
Deal, Carolyn D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (01) :34-43
[8]   Seroprevalence of Herpes Simplex Virus Types 1 and 2-United States, 1999-2010 [J].
Bradley, Heather ;
Markowitz, Lauri E. ;
Gibson, Theda ;
McQuillan, Geraldine M. .
JOURNAL OF INFECTIOUS DISEASES, 2014, 209 (03) :325-333
[9]   Acyclovir prophylaxis in late pregnancy prevents recurrent genital herpes and viral shedding [J].
Braig, S ;
Luton, D ;
Sibony, O ;
Edlinger, C ;
Boissinot, C ;
Blot, P ;
Oury, JF .
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2001, 96 (01) :55-58
[10]   A randomised placebo controlled trial of suppressive acyclovir in late pregnancy in women with recurrent genital herpes infection [J].
Brocklehurst, P ;
Kinghorn, G ;
Carney, O ;
Helsen, K ;
Ross, E ;
Ellis, E ;
Shen, R ;
Cowan, F ;
Mindel, A .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1998, 105 (03) :275-280