Sensitivity of the early luteal phase ovine cervix to prostaglandin E2 (PGE2) and expression of EP3 receptor mRNA

被引：5

作者：

Audicana, L ^{[1
]}

Aughey, E ^{[1
]}

O'Shaughnessy, PJ ^{[1
]}

机构：

[1] Univ Glasgow, Sch Vet, Dept Vet Preclin Sci, Vet Reprod Res Grp, Glasgow G61 1QH, Lanark, Scotland

来源：

RESEARCH IN VETERINARY SCIENCE | 1998年 / 64卷 / 02期

关键词：

D O I：

10.1016/S0034-5288(98)90016-9

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The effects and mechanism of action of prostaglandin E-2 (PGE(2)) on the ovine cervix are largely unknown in the luteal phase. In these studies we have shown that low levels of EP3-receptor (EP3R) mRNA are present in the ovine cervix and that the PGE(2) induces activation of polymorphonuclear leukocytes in the ovine cervix on day 6 of the oestrous cycle. It is possible, therefore, that PGE(2) acts on the ovine cervix through coupling to EP3 receptors.

引用

页码：177 / 179

页数：3

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