Management of Locally Advanced Gastroesophageal Cancer Still a Multidisciplinary Global Challenge?

被引:16
作者
Al-Batran, Salah-Eddin [1 ]
Lorenzen, Sylvie [2 ]
机构
[1] UCT Univ Canc Ctr, Krankenhaus Nordwest, Inst Clin Canc Res, Steinbacher Hohl 2-26, D-60488 Frankfurt, Germany
[2] Tech Univ Munich, Klinikum Rechts Isar, Dept Hematol & Oncol, Ismaninger Str 22, D-81675 Munich, Germany
关键词
Gastroesophageal cancer; Perioperative; Locally advanced; Chemotherapy; RESECTED GASTRIC-CANCER; PHASE-III TRIAL; NEOADJUVANT CHEMOTHERAPY; PERIOPERATIVE CHEMOTHERAPY; ESOPHAGOGASTRIC ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; 7TH EDITION; SURGERY; MULTICENTER; JUNCTION;
D O I
10.1016/j.hoc.2017.01.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The outcome of patients with locally advanced, resectable gastric cancer, or adenocarcinoma of the gastroesophageal junction is poor. In clinical trials, multimodality therapy, such as perioperative chemotherapy, preoperative or postoperative chemoradiation, or adjuvant chemotherapy led to significant increments in survival. Therefore, experts agree that patients with stage II or III disease should be offered a multidisciplinary treatment approach. However, patients are treated somewhat differently in the different regions of the world and survival rates remain far from being satisfactory. Efforts to further improve outcome are highly warranted.
引用
收藏
页码:441 / +
页数:13
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