Sedentary behaviour as a new behavioural target in the prevention and treatment of type 2 diabetes

被引:61
作者
Henson, Joseph [1 ,2 ]
Dunstan, David W. [3 ,4 ]
Davies, Melanie J. [1 ,2 ]
Yates, Thomas [1 ,2 ]
机构
[1] NIHR Leicester Loughborough Diet, Biomed Res Unit, Lifestyle & Phys Act, Leicester, Leics, England
[2] Univ Leicester, Diabet Res Ctr, Leicester, Leics, England
[3] Baker IDI Heart & Diabet Inst, Melbourne, Vic, Australia
[4] Australian Catholic Univ, Mary MacKillop Inst Hlth Res, Melbourne, Vic, Australia
关键词
sedentary behaviour; type 2 diabetes mellitus; glucose; insulin; ALL-CAUSE MORTALITY; PHYSICAL-ACTIVITY; CARDIOVASCULAR-DISEASE; SITTING TIME; CARDIORESPIRATORY FITNESS; POSTPRANDIAL GLYCEMIA; INSULIN SENSITIVITY; METABOLIC RISK; UNITED-STATES; NORMAL-WEIGHT;
D O I
10.1002/dmrr.2759
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Our modern day society encompasses an ecological niche in which sedentary behaviour, labour-saving devices and energy dense foods have become the new reference of living. We now spend more time sedentary, defined as sitting, than in all other activities combined. It has recently been confirmed that the consequences of our modern chair dependency are substantial and a direct contributing factor to the ever increasing epidemic of chronic diseases witnessed within industrialized environments. Epidemiological evidence - from both cross-sectional and prospective observational studies - has indicated that the time spent in sedentary behaviour is a distinct risk factor for several health outcomes, including type 2 diabetes mellitus, insulin resistance, all-cause and cardiovascular disease mortality, depression and some types of cancer. Importantly, these detrimental associations remain even after accounting for time spent in moderate-to-vigorous physical activity, with the strongest and most persistent associations seen between sedentary time and type 2 diabetes mellitus. Importantly, experimental studies have started to confirm the observational associations, with mounting evidence showing that breaking prolonged sitting time with light ambulation is an effective strategy for improving postprandial glucose regulation. Indeed, there is even emerging evidence showing that simply substituting sitting for standing regularly throughout the day may be of sufficient stimulus to improve glucose regulation. We highlight some of the key definitions, issues and evidence underpinning the link between sedentary behaviour and chronic disease in order to better inform clinicians and patients about the importance of incorporating reduced sitting time into type 2 diabetes mellitus management and prevention pathways. Copyright (c) 2016 John Wiley & Sons, Ltd.
引用
收藏
页码:213 / 220
页数:8
相关论文
共 59 条
  • [1] 2011 Compendium of Physical Activities: A Second Update of Codes and MET Values
    Ainsworth, Barbara E.
    Haskell, William L.
    Herrmann, Stephen D.
    Meckes, Nathanael
    Bassett, David R., Jr.
    Tudor-Locke, Catrine
    Greer, Jennifer L.
    Vezina, Jesse
    Whitt-Glover, Melicia C.
    Leon, Arthur S.
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2011, 43 (08) : 1575 - 1581
  • [2] [Anonymous], AUSTR PHYS ACT SED B
  • [3] Breaking up prolonged sitting with light-intensity walking improves postprandial glycemia, but breaking up sitting with standing does not
    Bailey, Daniel P.
    Locke, Christopher D.
    [J]. JOURNAL OF SCIENCE AND MEDICINE IN SPORT, 2015, 18 (03) : 294 - 298
  • [4] Exercise training can modify the natural history of diabetic peripheral neuropathy
    Balducci, Stefano
    Iacobellis, Gianluca
    Parisi, Leoluca
    Di Biase, Nicolina
    Calandriello, Eugenio
    Leonetti, Frida
    Fallucca, Francesco
    [J]. JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2006, 20 (04) : 216 - 223
  • [5] Barnes J, 2012, APPL PHYSIOL NUTR ME, V37, P540, DOI [10.1139/h2012-024, 10.1139/H2012-024]
  • [6] Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults A Systematic Review and Meta-analysis
    Biswas, Aviroop
    Oh, Paul I.
    Faulkner, Guy E.
    Bajaj, Ravi R.
    Silver, Michael A.
    Mitchell, Marc S.
    Alter, David A.
    [J]. ANNALS OF INTERNAL MEDICINE, 2015, 162 (02) : 123 - +
  • [7] The sedentary office: an expert statement on the growing case for change towards better health and productivity
    Buckley, John P.
    Hedge, Alan
    Yates, Thomas
    Copeland, Robert J.
    Loosemore, Michael
    Hamer, Mark
    Bradley, Gavin
    Dunstan, David W.
    [J]. BRITISH JOURNAL OF SPORTS MEDICINE, 2015, 49 (21) : 1357 - 1362
  • [8] Standing-based office work shows encouraging signs of attenuating post-prandial glycaemic excursion
    Buckley, John P.
    Mellor, Duane D.
    Morris, Michael
    Joseph, Franklin
    [J]. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2014, 71 (02) : 109 - 111
  • [9] Trends over 5 Decades in US Occupation-Related Physical Activity and Their Associations with Obesity
    Church, Timothy S.
    Thomas, Diana M.
    Tudor-Locke, Catrine
    Katzmarzyk, Peter T.
    Earnest, Conrad P.
    Rodarte, Ruben Q.
    Martin, Corby K.
    Blair, Steven N.
    Bouchard, Claude
    [J]. PLOS ONE, 2011, 6 (05):
  • [10] Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes
    Church, TS
    LaMonte, MJ
    Barlow, CE
    Blair, SN
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (18) : 2114 - 2120