Enantioselective addition of diethylzinc to aromatic aldehydes with aminophenol as catalysts

被引：0

作者：

Li, XS ^{[1
]}

Shen, ZX ^{[1
]}

Ge, JF ^{[1
]}

Zhang, YW ^{[1
]}

机构：

[1] Suzhou Univ, Dept Chem & Chem Engn, Suzhou 215006, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 23卷 / 04期

关键词：

chiral; aminophenol; addition; diethylzinc;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four aminophenols have been prepared and evaluated as the catalysts for the enantioselective addition of diethylzinc to aromatic aldehydes. Ligand 1a was found to show the best asymmetric induction in the catalysis of the reaction of m-chlorobenzaldehyde to provide sec-alcohol with-high yield (95%) and moderate ee (57%).

引用

页码：387 / 389

页数：3

共 6 条

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