Anticoagulation in chronic liver disease

被引：41
作者：
Dhar, Ameet [1 ]
Mullish, Benjamin H. [1 ]
Thursz, Mark R. [1 ]
机构：
[1] Imperial Coll London, Div Digest Dis, Dept Surg & Canc, St Marys Hosp Campus, London, England
来源：
JOURNAL OF HEPATOLOGY | 2017年 / 66卷 / 06期
关键词：
Anticoagulation; Thrombosis; Cirrhosis; Heparin; Direct oral anticoagulants; Thromboembolism; Liver diseases; Teaching rounds; PORTAL-VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM PROPHYLAXIS; HOSPITALIZED CIRRHOSIS PATIENTS; CHRONIC HEPATITIS-C; FACTOR-V-LEIDEN; RISK-FACTORS; PHARMACOLOGICAL PROPHYLAXIS; ORAL ANTICOAGULANTS; IN-VITRO; FIBROSIS;
D O I：
10.1016/j.jhep.2017.01.006
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
In this Grand Round presentation, the case of a man with decompensated liver disease is described. He subsequently developed a fatal pulmonary embolism, which may not have occurred if he had been prescribed prophylactic anticoagulation to prevent venous thromboembolic disease. The burden of thrombotic disease in those with chronic liver disease is discussed, before a more detailed analysis of the current evidence, safety data, and clinical dilemmas regarding the use of anticoagulation in patients with chronic liver disease. Finally, the future directions within this field are explored. (C) 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：1313 / 1326
页数：14
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