Carp Proteins as a Source of Bioactive Peptides - an in Silico Approach

被引:19
作者
Darewicz, Malgorzata [1 ]
Borawska, Justyna [1 ]
Pliszka, Monika [1 ]
机构
[1] Univ Warmia & Mazury, Fac Food Sci, Dept Food Biochem, PL-10726 Olsztyn, Poland
关键词
biological activity; bioinformatics; BIOPEP; fish; databases; proteolysis; ACE INHIBITORY PEPTIDES; BIOPEP DATABASE; IDENTIFICATION; FISH; MEAT;
D O I
10.17221/300/2015-CJFS
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
In silico prediction methods and tools were used to determine whether bioactive peptides are hidden in the amino acid sequences of carp (Cyprinus carpio) proteins and whether they can be released after gastric, duodenal, and gastroduodenal in silico digestion. Fragments with 15 types of biological activity in intact proteins and, after gastrointestinal digestion, with 11 types of activity were identified. Angiotensin I-converting enzyme inhibitory (ACEi) and antioxidant peptides were the most predominant fragments of proteins in the group of intact proteins and in silico digests. After in silico digestion the highest number of sequences with ACEi activity (108) and antioxidant activity (13) was released after gastro-duodenal digestion of the myosin heavy chain.
引用
收藏
页码:111 / 117
页数:7
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