The Vascular Impairment of Cognition Classification Consensus Study

被引：143

作者：

Skrobot, Olivia A. ^{[1
]}

O'Brien, John ^{[2
]}

Black, Sandra ^{[3
]}

Chen, Christopher ^{[4
]}

DeCarli, Charles ^{[5
,6
,7
]}

Erkinjuntti, Timo ^{[8
,9
]}

Ford, Gary A. ^{[10
]}

Kalaria, Rajesh N. ^{[11
]}

Pantoni, Leonardo ^{[12
]}

Pasquier, Florence ^{[13
]}

Roman, Gustavo C. ^{[14
]}

Wallin, Anders ^{[15
]}

Sachdev, Perminder ^{[16
,17
]}

Skoog, Ingmar ^{[18
]}

Ben-Shlomo, Yoav ^{[19
]}

Passmore, Anthony P. ^{[20
]}

Love, Seth ^{[1
]}

Kehoe, Patrick G. ^{[1
]}

Taragano, F. E. ^{[21
,22
]}

Kril, J. ^{[23
]}

Cavalieri, M. ^{[24
]}

Jellinger, K. A. ^{[25
]}

Kovacs, G. G. ^{[26
]}

Engelborghs, S. ^{[27
]}

Lafosse, C. ^{[28
,29
]}

Bertolucci, P. H. ^{[30
]}

Brucki, S. ^{[31
]}

Caramelli, P. ^{[32
]}

Alves, T. C. de Toledo Ferraz ^{[33
]}

Bocti, C. ^{[34
]}

Fulop, T. ^{[35
]}

Hogan, D. B.

Hsiung, G. R. ^{[36
]}

Kirk, A. ^{[37
]}

Leach, L. ^{[38
]}

Robillard, A. ^{[39
]}

Sahlas, D. J. ^{[40
]}

Guo, Q. ^{[41
]}

Tian, J.

Hokkanen, L. ^{[42
]}

Jokinen, H. ^{[43
]}

Benisty, S. ^{[44
]}

Deramecourt, V. ^{[45
]}

Hauw, J. ^{[46
,47
]}

Lenoir, H. ^{[48
,49
]}

Tsatali, M. ^{[50
]}

Tsolaki, M.

Sundar, U. ^{[51
]}

Coen, R. F. ^{[52
]}

Korczyn, A. D. ^{[53
]}

机构：

[1] Univ Bristol, Sch Clin Sci, Southmead Hosp, Dementia Res Grp,Fac Hlth Sci, Bristol, Avon, England

[2] Univ Cambridge, Sch Clin Med, Dept Psychiat, Cambridge, England

[3] Univ Toronto, Sunnybrook Res Inst, Toronto, ON, Canada

[4] Natl Univ Singapore, Memory Aging & Cognit Ctr, Dept Pharmacol, Singapore, Singapore

[5] Univ Calif Davis, Alzheimers Dis Ctr, Sacramento, CA 95817 USA

[6] Univ Calif Davis, Dept Neurol, Imaging Dementia & Aging IDeA Lab, Sacramento, CA 95817 USA

[7] Univ Calif Davis, Ctr Neurosci, Sacramento, CA 95817 USA

[8] Univ Helsinki, Clin Neurosci, Neurol, Helsinki, Finland

[9] Helsinki Univ Hosp, HUS, Helsinki, Finland

[10] Univ Oxford, Div Med Sci, Oxford, England

[11] Inst Neurosci, Newcastle Upon Tyne, Tyne & Wear, England

[12] Univ Florence, Dept Neurosci, Area Drug & Child Hlth NEUROFARBA, Florence, Italy

[13] Univ Lille, INSERM, CHU Lille, U1171,Degenerat & Vasc Cognit Disorders, F-U1171 Lille, France

[14] Methodist Neurol Inst, Houston, TX USA

[15] Univ Gothenburg, Sahlgrenska Univ Hosp, Inst Neurosci & Physiol, Sahlgrenska Acad,Memory Clin,Dept Neuropsychiat, Molndal, Sweden

[16] Univ New South Wales, Sch Psychiat, Sydney, NSW, Australia

[17] Prince Wales Hosp, Neuropsychiat Inst, CHeBA Ctr Hlth Brain Ageing, Randwick, NSW, Australia

[18] Univ Gothenburg, Ctr Hlth & Ageing AGECAP, Sahlgrenska Acad, Inst Neurosci & Physiol, Gothenburg, Sweden

[19] Univ Bristol, Sch Social & Community Med, Bristol, Avon, England

[20] Queens Univ Belfast, Inst Clin Sci, Royal Victoria Hosp, Belfast, Antrim, North Ireland

[21] CONICET Natl Res Council, Buenos Aires, DF, Argentina

[22] CEMIC Univ Hosp, Buenos Aires, DF, Argentina

[23] Univ Sydney, Sydney, NSW 2006, Australia

[24] Med Univ Graz, Graz, Austria

[25] Inst Clin Neurobiol, Graz, Austria

[26] Med Univ Vienna, Vienna, Austria

[27] Univ Antwerp, Antwerp, Belgium

[28] RevArte Rehabil Hosp, Antwerp, Belgium

[29] Katholieke Univ Leuven, Leuven, Belgium

[30] Univ Fed Sao Paulo, Sao Paulo, Brazil

[31] Univ Sao Paulo, Sao Paulo, Brazil

[32] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil

[33] Dept Psychiat Sao Paulo Med Sch, Sao Paulo, Brazil

[34] Univ Sherbrooke, Sherbrooke, PQ, Canada

[35] Univ Calgary, Calgary, AB, Canada

[36] Univ British Columbia, Vancouver, BC, Canada

[37] Univ Saskatchewan, Saskatoon, SK, Canada

[38] York Univ, Glendon Coll, Toronto, ON, Canada

[39] Hop Maisonneuve, Montreal, PQ, Canada

[40] McMaster Univ, Hamilton, ON, Canada

[41] Fudan Univ, Huashan Hosp, Shanghai, Peoples R China

[42] Univ Helsinki, Helsinki, Finland

[43] Helsinki Univ Hosp, Helsinki, Finland

[44] Inst Natl Invalides, Woippy, France

[45] Lille Univ Hosp, Lille, France

[46] Hop La Pitie Salpetriere, APHP, Paris, France

[47] Pierre & Marie Curie Univ, Paris, France

[48] Broca Hosp, HUPC APHP, Paris, France

[49] Paris Descartes 5 Univ, Paris, France

[50] Greek Alzheimer Assoc, Thessaloniki, Greece

来源：

ALZHEIMERS & DEMENTIA | 2017年 / 13卷 / 06期

基金：

英国工程与自然科学研究理事会;

关键词：

Vascular cognitive impairment; Vascular dementia; Guidelines; Criteria; Consensus; Delphi; ALZHEIMERS-DISEASE; DIAGNOSTIC-CRITERIA; MIXED DEMENTIA; DISORDERS; LESSONS; RISK;

D O I：

10.1016/j.jalz.2016.10.007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment. Methods: The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines. Results: VICCCS had a mean of 122 (98-153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge. Discussion: VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research. (C) 2016 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

引用

页码：624 / 633

页数：10

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