Evaluation of the in vitro activity of daptomycin against 19615 clinical isolates of Gram-positive cocci collected in North American hospitals (2002-2005)

被引：56
|
作者：
Pfaller, Michael A.
Sader, Helio S. [1 ]
Jones, Ronald N.
机构：
[1] JML Labs, N Liberty, IA 52317 USA
[2] Univ Iowa, Iowa City, IA 52242 USA
[3] Univ Fed Sao Paulo, Div Infect Dis, BR-04023900 Sao Paulo, Brazil
[4] Tufts Univ, Sch Med, Boston, MA 02111 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2007年 / 57卷 / 04期
关键词：
daptomycin; gram-positive infections; Staphylococcus aureus; susceptibility;
D O I：
10.1016/j.diagmicrobio.2006.10.007
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We evaluated the antimicrobial activity of daptomycin against 19 615 clinical strains consecutively collected by numerous centers located across the United States and Canada (2002-2005). Daptomycin was very active against all indicated species (>99% susceptible), with the highest MIC results being 2, 8, 0.5, and 1 mu g/mL for staphylococci, enterococci, beta-hemolytic streptococci, and viridans group streptococci, respectively, and no significant loss in potency was observed over the period studied. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：459 / 465
页数：7
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