Genetic Relationships among Reptilian and Mammalian Campylobacter fetus Strains Determined by Multilocus Sequence Typing

被引:26
作者
Dingle, Kate E. [1 ]
Blaser, Martin J. [2 ]
Tu, Zheng-Chao [2 ]
Pruckler, Janet [3 ]
Fitzgerald, Collette [3 ]
van Bergen, Marcel A. P. [4 ,7 ,8 ,9 ,10 ]
Lawson, Andrew J. [5 ]
Owen, Robert J. [5 ]
Wagenaar, Jaap A. [4 ,6 ,7 ,8 ,9 ,10 ]
机构
[1] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Lab Sci, Oxford OX3 9DU, England
[2] NYU, Sch Med, Dept Med, New York, NY 10016 USA
[3] CDC, Enter Dis Lab Branch, Atlanta, GA 30333 USA
[4] Cent Vet Inst Wageningen UR, NL-8200 AB Lelystad, Netherlands
[5] Hlth Protect Agcy, Lab Enter Pathogens, Ctr Infect, London, England
[6] Univ Utrecht, Fac Vet Med, Dept Immunol & Infect Dis, Utrecht, Netherlands
[7] WHO Collaborating Ctr Campylobacter, Lelystad, Netherlands
[8] OIE Reference Lab Campylobacteriosis, Lelystad, Netherlands
[9] WHO Collaborating Ctr Campylobacter, Utrecht, Netherlands
[10] OIE Reference Lab Campylobacteriosis, Utrecht, Netherlands
基金
英国惠康基金;
关键词
PATHOGENESIS; JEJUNI; RECOMBINATION; HOMOLOGS; LOCUS;
D O I
10.1128/JCM.01439-09
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Reptile Campylobacter fetus isolates and closely related strains causing human disease were characterized by multilocus sequence typing. They shared similar to 90% nucleotide sequence identity with classical mammalian C. fetus, and there was evidence of recombination among members of these two groups. The reptile group represents a possible separate genomospecies capable of infecting humans.
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收藏
页码:977 / 980
页数:4
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