Evaluation of the analgesic and CNS actions of different fractions from the methanol extract of Teucrium flavum L.

被引:0
作者
Bello, R
Beltran, B
Moreno, L
Calatayud, S
Primo-Yufera, E
Esplugues, J
机构
[1] Univ Valencia, Fac Med & Odontol, Dept Farmacol, Valencia 46010, Spain
[2] Univ Politecn Valencia, Escuela Tecn Super Ingn Agronomos, Dept Biotecnol, Valencia 46022, Spain
关键词
Teucrium flavum L; fractions; analgesia; effect on CNS;
D O I
10.1002/(SICI)1099-1573(19980201)12:1<65::AID-PTR187>3.0.CO;2-N
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Different fractions (F-1, F-3, F-5, F-6, F-7, F-8) of the methanol extract from Teucrium flavum L. have been tested for their central nervous system and analgesic activities at a dose of 200 mg/kg. Fractions F-1, F-3 and F-7 showed CNS depressant activity, while fractions F-5, F-6 and F-8 had a slight CNS stimulant action. Fractions F-5, F-6, F-7 and F-8 were responsible for the analgesic activity of the extract. (C) 1998 John Wiley & Sons, Ltd.
引用
收藏
页码:65 / 67
页数:3
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