The contribution of germline DNA damage response mutations on prostate cancer risk and prognosis: A UK Biobank whole-exome analysis.

被引:0
|
作者
Camacho, Niedzica [1 ]
Matakidou, Athena [1 ]
机构
[1] AstraZeneca, Cambridge, England
关键词
D O I
10.1200/JCO.2021.39.6_suppl.67
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
67
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Germline DNA Repair Mutations and Response to Hormonal Therapy in Advanced Prostate Cancer
    Antonarakis, Emmanuel S.
    EUROPEAN UROLOGY, 2017, 72 (01) : 43 - 44
  • [22] ASSOCIATION OF KIDNEY CANCER WITH BOTH NOVEL AND REPORTED MONOGENIC GENE MUTATIONS: RESULTS OF WHOLE EXOME SEQUENCING IN THE UK BIOBANK
    Wei, Jun
    Novakovic, Kristian
    Shi, Zhuqing
    Rifkin, Andrew
    Zheng, S. Lilly
    Helfand, Brian
    Xu, Jianfeng
    JOURNAL OF UROLOGY, 2023, 209 : E559 - E559
  • [23] The contribution of rare and common genetic variants to risk of prostate cancer and second primary cancer after prostate in the UK Biobank
    Beebe-Dimmer, Jennifer Lynn
    Snyder, Nathan
    Schwartz, Ann G.
    Wei, Jun
    Shi, Zhuqing
    Tran, Huy
    Zheng, Lily
    Shevach, Jeffrey
    Cooney, Kathleen A.
    Xu, Jianfeng
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [24] Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies
    Tlemsani, Camille
    Takahashi, Nobuyuki
    Pongor, Lorinc
    Rajapakse, Vinodh N.
    Tyagi, Manoj
    Wen, Xinyu
    Fasaye, Grace-Ann
    Schmidt, Keith T.
    Desai, Parth
    Kim, Chul
    Rajan, Arun
    Swift, Shannon
    Sciuto, Linda
    Vilimas, Rasa
    Webb, Santhana
    Nichols, Samantha
    Figg, William Douglas
    Pommier, Yves
    Calzone, Kathleen
    Steinberg, Seth M.
    Wei, Jun S.
    Guha, Udayan
    Turner, Clesson E.
    Khan, Javed
    Thomas, Anish
    SCIENCE TRANSLATIONAL MEDICINE, 2021, 13 (578)
  • [25] Whole-exome sequencing analysis of urine transrenal tumor DNA in metastatic colorectal cancer patients
    Crisafulli, Giovanni
    Mussolin, Benedetta
    Cassingena, Andrea
    Montone, Monica
    Bartolini, Alice
    Barault, Ludovic
    Martinetti, Antonio
    Morano, Federica
    Pietrantonio, Filippo
    Sartore-Bianchi, Andrea
    Siena, Salvatore
    Di Nicolatonio, Federica
    Marsoni, Silvia
    Bardelli, Alberto
    Siravegna, Giulia
    CLINICAL CANCER RESEARCH, 2020, 26 (11) : 75 - 75
  • [26] Imputation-Powered Whole-Exome Analysis Identifies Rare Coding Variants and Genes Associated With Kidney Function and Disease in the UK Biobank
    Katsara, Maria-Alexandra
    Konig, Eva
    Wuttke, Matthias
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 576 - 576
  • [27] Germline mutations in DNA repair genes are associated with bladder cancer risk and unfavourable prognosis
    Na, Rong
    Wu, Yishuo
    Jiang, Guangliang
    Yu, Hongjie
    Lin, Xiaoling
    Wang, Meilin
    Conran, Carly A.
    Fantus, Richard J.
    Zhang, Ning
    Liu, Shenghua
    Helfand, Brian T.
    Zheng, Siqun L.
    Isaacs, William B.
    Ding, Qiang
    Shen, Zhoujun
    Xu, Jianfeng
    BJU INTERNATIONAL, 2018, 122 (05) : 808 - 813
  • [28] Protein-truncating and rare missense variants in ATM and CHEK2 and associations with cancer in UK Biobank whole-exome sequence data
    Mukhtar, Toqir K.
    Wilcox, Naomi
    Dennis, Joe
    Yang, Xin
    Naven, Marc
    Mavaddat, Nasim
    Perry, John R. B.
    Gardner, Eugene
    Easton, Douglas F.
    JOURNAL OF MEDICAL GENETICS, 2024, 61 (11) : 1016 - 1022
  • [29] Whole-exome sequencing reveals a comprehensive germline mutation landscape and identifies twelve novel predisposition genes in Chinese prostate cancer patients
    Liang, Yonghao
    Chiu, Peter Ka-Fung
    Zhu, Yao
    Wong, Christine Yim-Ping
    Xiong, Qing
    Wang, Lin
    Teoh, Jeremy Yuen-Chun
    Cao, Qin
    Wei, Yu
    Ye, Ding-Wei
    Tsui, Stephen Kwok-Wing
    Ng, Chi-Fai
    PLOS GENETICS, 2022, 18 (09):
  • [30] Defining germline mutations of DNA damage repair genes in African American prostate cancer patients
    Babcock, Kevin
    Zhang, Xijun
    Wilkerson, Matthew
    Dalgard, Clifton L.
    Tan, Shyh-Han
    Ravindranath, Lakshmi
    Chen, Yongmei
    Cullen, Jennifer
    Srivastava, Shiv
    Rosner, Inger L.
    Petrovics, Gyorgy
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2020, 29 (06)