Meta analysis of the correlation between Helicobacter pylori infection and coronary heart disease

被引：0
|
作者：
Chen, Qiansheng [1 ]
Huang, Meihua [2 ]
Chen, Kaihong [1 ]
Fang, Yong [1 ]
Li, Weiguo [1 ]
Li, Ganyang [1 ]
Chen, Liling [1 ]
Jiang, Tianrong [2 ]
Lan, Shiqian [2 ]
Lin, Dong [3 ]
机构：
[1] First Hosp, Cardiovasc Dept Internal Med, Longyan 364000, Fujian Province, Peoples R China
[2] First Hosp, Endoscope Ctr, Longyan 364000, Fujian Province, Peoples R China
[3] First Hosp, Gastrointestinal Dept Internal Med, Longyan 364000, Fujian Province, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2016年 / 9卷 / 02期
关键词：
Coronary artery disease; myocardial infarction; Helicobacter pylori; infection; Meta analysis;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objective: To investigate the relationship between Helicobacter pylori infection and coronary heart disease. Methods: Pubmed, Medline and Embase databases were retrieved by a computer. Studies published in English from January 2000 to June 2015 that reported on association between coronary heart disease and infection of helicobacter pylori were selected. Meta analysis was used to evaluate the combined OR value and the 95% confidence interval (95% CI) after merging. Results: There were 18 studies included in this Meta analysis, the combined OR was 1.64 and 95% CI was 1.22-2.23 that calculated by a random effect model. 12 studies on association between coronary heart disease and Helicobacter pylori infection were collected. The Meta analysis showed that there was a certain relationship between the coronary heart disease and Helicobacter pylori infection, and the combined OR was 1.96, 95% CI was 1.28-3.02. Conclusion: Infection with helicobacter pylori was associated with coronary heart disease. Therefore, health education should be strengthened to reduce the chance of helicobacter pylori infection and prevent the occurrence of coronary heart disease.
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收藏
页码：1396 / 1402
页数：7
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