Transfusion trigger: when to transfuse?

被引:23
作者
Marshall, JC [1 ]
机构
[1] Univ Toronto, Toronto, ON, Canada
来源
CRITICAL CARE | 2004年 / 8卷 / Suppl 2期
关键词
blood transfusion; hemoglobin level; tissue oxygenation;
D O I
10.1186/cc2846
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivists' transfusion practices. Conventional transfusion triggers of 100 g/l have been challenged by reports indicating that aerobic metabolism is supported by hemoglobin levels of 50 g/l or less. Evidence from randomized trials also indicates that withholding transfusions may result in improved outcomes. Arbitrary numeric hemoglobin triggers, however, cannot supercede intervention based on individual physiologic need and clinical circumstances.
引用
收藏
页码:S31 / S33
页数:3
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