The therapeutic efficacy of allyl isothiocyanate in cows with bovine digital dermatitis

被引：3

作者：

Chiba, Kanako ^{[1
]}

Miyazaki, Tamako ^{[1
]}

Sekiyama, Yasushi ^{[2
]}

Miyazaki, Masao ^{[3
]}

Okada, Keiji ^{[1
]}

机构：

[1] Iwate Univ, Cooperat Dept Vet Med, Fac Agr, 3-18-8 Ueda, Morioka, Iwate 0208550, Japan

[2] Mitsubishi Kagaku Foods Corp, Chiyoda Ku, 1-1-1 Marunouchi, Tokyo 1008251, Japan

[3] Iwate Univ, Dept Biol Chem & Food Sci, Fac Agr, 3-18-8 Ueda, Morioka, Iwate 0208550, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2017年 / 79卷 / 07期

关键词：

allyl isothiocyanate; bovine digital dermatitis; non-antibiotic treatment; treponema; TOPICAL TREATMENT; DAIRY-CATTLE; CAMPYLOBACTER-JEJUNI; CALIFORNIA DAIRY; OXYTETRACYCLINE; PERFORMANCE; INHIBITION; FOOTWARTS; LESIONS; COPPER;

D O I：

10.1292/jvms.16-0270

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Bovine digital dermatitis (BDD) is the most prevalent infectious cause of lameness in cattle. Because Treponema infection is a major etiology of BDD, the most common treatment of BDD is an antibiotic. Nonetheless, dairy cows require a withdrawal period after antibiotic treatment before their milk can be marketed. To address the problem, in this study, we tested whether 3 nonantibiotic agents (used separately)-allyl isothiocyanate (AITC), sodium alginate, and calcium hydroxide-alleviate BDD lesions in dairy cows. The AITC treatment improved the BDD lesions, whereas the sodium alginate and calcium hydroxide treatments did not. Therapeutic efficacy of AITC was similar to that of lincomycin, a topical antibiotic prescribed for BDD. These results suggest that AITC is a promising nonantibiotic agent for BDD treatment in dairy cows.

引用

页码：1191 / 1195

页数：5

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