Palladium-catalyzed N-arylation of N,N-dialkylhydrazines with aryl chlorides

被引：12

作者：

Cacchi, Sandro ^{[1
]}

Fabrizi, Giancarlo ^{[1
]}

Goggiamani, Antonella ^{[1
]}

Sgalla, Simona ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biologi, I-00185 Rome, Italy

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 03期

关键词：

aryl chlorides; carbon-nitrogen bond forming reaction; hydrazines; palladium;

D O I：

10.1002/adsc.200600299

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

NN-Dialkyl-N'-arylhydrazines have been prepared usually in high to excellent yields via the reaction of N,N-dialkylhydrazines with aryl chlorides in the presence of Pd-2(dba)(3), Xphos and NaO-t-Bu in dioxane at 120 degrees C. With ortho-substituted aryl chlorides best results have been obtained by using 2-(2',6'-dimethoxybiphenyl)dicyclohexylphosphine (ligand d) as the ligand.

引用

页码：453 / 458

页数：6

共 4 条

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ORGANIC LETTERS, 2005, 7 (08) :1497-1500

[2]

Galardon E, 2002, ANGEW CHEM INT EDIT, V41, P1760, DOI 10.1002/1521-3773(20020517)41:10<1760::AID-ANIE1760>3.0.CO

[3]

2-3

[4] Air-stable trialkylphosphonium salts: Simple, practical, and versatile replacements for air-sensitive trialkylphosphines. Applications in stoichiometric and catalytic processes [J].

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ORGANIC LETTERS, 2001, 3 (26) :4295-4298

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