Stenotrophomonas maltophilia in a university hospital of traditional Chinese medicine: molecular epidemiology and antimicrobial resistance

被引：11
|
作者：
Zhao, S. [1 ]
Yang, L. [1 ]
Liu, H. [1 ]
Gao, F. [1 ]
机构：
[1] Nanjing Univ Chinese Tradit Med, Affiliated Hosp, Dept Lab Med, 155th Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China
来源：
JOURNAL OF HOSPITAL INFECTION | 2017年 / 96卷 / 03期
关键词：
Antibiotic resistance; Stenotrophomonas maltophilia; Molecular epidemiology; INTEGRONS; GENES;
D O I：
10.1016/j.jhin.2017.04.001
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Stenotrophomona maltophilia has emerged as an important opportunistic pathogen that is highly antibiotic resistant. Analysis of antibiotic susceptibilities, drug-resistant gene profiles and molecular typing of S. maltophilia was undertaken in a university hospital of traditional Chinese medicine in East China. Resistance to sulphamethoxazole (SXT) was found to be an indicator of multi-drug resistance. SXT resistance was mediated by sul and dfrA genes in integrons, especially class 1. Some evidence of clonal dissemination was found, indicating the occurrence of cross-transmission of antibiotic-resistant strains within the hospital. This underscores the need for effective control and prevention measures in hospitals. (C) 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：286 / 289
页数：4
相关论文
共 50 条
  • [41] Emergence of fluoroquinolone-resistant Stenotrophomonas maltophilia in blood isolates causing bacteremia: molecular epidemiology and microbiologic characteristics
    Cha, Min Kyeong
    Kang, Cheol-In
    Kim, So Hyun
    Cho, Sun Young
    Ha, Young Eun
    Chung, Doo Ryeon
    Peck, Kyong Ran
    Song, Jae-Hoon
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2016, 85 (02) : 210 - 212
  • [42] Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics
    Blanco, Paula
    Hjort, Karin
    Martinez, Jose L.
    Andersson, Dan, I
    MSPHERE, 2020, 5 (05)
  • [43] Stenotrophomonas maltophilia outbreak in a university hospital: epidemiological investigation and literature review of an emerging healthcare-associated infection
    Erinmez, Mehmet
    Askin, Feyza Nur
    Zer, Yasemin
    REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, 2024, 66
  • [44] Antimicrobial susceptibility profile of molecular typed cystic fibrosis Stenotrophomonas maltophilia isolates and differences with noncystic fibrosis isolates
    Cantón, R
    Valdezate, S
    Vindel, A
    Del Saz, BS
    Maíz, L
    Baquero, F
    PEDIATRIC PULMONOLOGY, 2003, 35 (02) : 99 - 107
  • [45] Diversity of L1/L2 genes and molecular epidemiology of high-level carbapenem resistance Stenotrophomonas maltophilia isolates from animal production environment in China
    Han, Lu
    Zhang, Rong-Min
    Jia, Ling
    Bai, Shuan-Cheng
    Liu, Xu-Wei
    Wei, Ran
    Cui, Chao-Yue
    Sun, Ruan-Yang
    Wang, Min-Ge
    Cai, Da-Tong
    Liao, Xiao-Ping
    Liu, Ya-Hong
    Sun, Jian
    INFECTION GENETICS AND EVOLUTION, 2020, 86
  • [46] Epidemiology and molecular characterization of the antimicrobial resistance of Pseudomonas aeruginosa in Chinese mink infected by hemorrhagic pneumonia
    Bai, Xue
    Liu, Siguo
    Zhao, Jianjun
    Cheng, Yuening
    Zhang, Hailing
    Hu, Bo
    Zhang, Lei
    Shi, Qiumei
    Zhang, Zhiqiang
    Wu, Tonglei
    Luo, Guoliang
    Lian, Shizhen
    Xu, Shujuan
    Wang, Jianke
    Zhang, Wanjiang
    Yan, Xijun
    CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE, 2019, 83 (02): : 122 - 132
  • [47] Molecular Epidemiology and Antimicrobial Resistance of Outbreaks of Klebsiella pneumoniae Clinical Mastitis in Chinese Dairy Farms
    Fu, Shaodong
    Wen, Chen
    Wang, Zhenglei
    Qiu, Yawei
    Zhang, Yihao
    Zuo, Jiakun
    Xu, Yuanyuan
    Han, Xiangan
    Luo, Zhenhua
    Chen, Wei
    Miao, Jinfeng
    MICROBIOLOGY SPECTRUM, 2022, 10 (06):
  • [48] Antimicrobial resistance, genetic characterization, and molecular epidemiology ofUreaplasmaspecies in males with infertility
    Zhao, Lihong
    Liu, Aihua
    Li, Ruiying
    Zhao, Shuping
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2020, 39 (11) : 2177 - 2183
  • [49] Molecular epidemiology and antimicrobial resistance patterns of carbapenem-resistant Acinetobacter baumannii isolates from patients admitted at ICUs of a teaching hospital in Zunyi, China
    Xiong, Lin
    Deng, Chengmin
    Yang, Guangwu
    Shen, Meijing
    Chen, Benhai
    Tian, Rengui
    Zha, He
    Wu, Kaifeng
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2023, 13
  • [50] Clonal Diversity, Biofilm Formation, and Antimicrobial Resistance among Stenotrophomonas maltophilia Strains from Cystic Fibrosis and Non-Cystic Fibrosis Patients
    Pompilio, Arianna
    Savini, Vincenzo
    Fiscarelli, Ersilia
    Gherardi, Giovanni
    Di Bonaventura, Giovanni
    ANTIBIOTICS-BASEL, 2020, 9 (01):
12345