Stenotrophomonas maltophilia in a university hospital of traditional Chinese medicine: molecular epidemiology and antimicrobial resistance

被引：11
|
作者：
Zhao, S. [1 ]
Yang, L. [1 ]
Liu, H. [1 ]
Gao, F. [1 ]
机构：
[1] Nanjing Univ Chinese Tradit Med, Affiliated Hosp, Dept Lab Med, 155th Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China
来源：
JOURNAL OF HOSPITAL INFECTION | 2017年 / 96卷 / 03期
关键词：
Antibiotic resistance; Stenotrophomonas maltophilia; Molecular epidemiology; INTEGRONS; GENES;
D O I：
10.1016/j.jhin.2017.04.001
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Stenotrophomona maltophilia has emerged as an important opportunistic pathogen that is highly antibiotic resistant. Analysis of antibiotic susceptibilities, drug-resistant gene profiles and molecular typing of S. maltophilia was undertaken in a university hospital of traditional Chinese medicine in East China. Resistance to sulphamethoxazole (SXT) was found to be an indicator of multi-drug resistance. SXT resistance was mediated by sul and dfrA genes in integrons, especially class 1. Some evidence of clonal dissemination was found, indicating the occurrence of cross-transmission of antibiotic-resistant strains within the hospital. This underscores the need for effective control and prevention measures in hospitals. (C) 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：286 / 289
页数：4
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