A Direct Access to N-Arylation of Guanidines by Ligand-free, Copper Catalysis at Room Temperature

被引：9

作者：

Nematpour, Manijeh ^{[1
]}

Abedi, Elham ^{[2
]}

Abedi, Elahe ^{[3
]}

机构：

[1] Islamic Azad Univ, Sci & Res Branch, Young Researchers & Elites Club, Tehran, Iran

[2] Shiraz Univ Med Siences, Pathol Dept, Shiraz, Iran

[3] Shiraz Univ Med Sci, Dept Hyg & Qual Control Food Sci, Shiraz, Iran

来源：

LETTERS IN ORGANIC CHEMISTRY | 2018年 / 15卷 / 08期

关键词：

N-Arylation; ullmann coupling; guanidine; copper-catalyzed; aryl halides; organic; CHEMISTRY; AMIDINES;

D O I：

10.2174/1570178615666171222162430

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The copper (I)-catalyzed cross-coupling reactions between aryl halides and guanidines to produce N-aryl guanidines have been developed. Mild reaction conditions, good yields, ligand-free, easy work-up, no column chromatography, and ease of handling at room temperature are the main aspects of the method.

引用

页码：678 / 681

页数：4

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