The renin-angiotensin system in the bovine utero-placental unit

被引：0

作者：

Nielsen, AH ^{[1
]}

Schauser, KH ^{[1
]}

Winther, H ^{[1
]}

Dantzer, V ^{[1
]}

Poulsen, K ^{[1
]}

机构：

[1] Royal Vet & Agr Univ, Dept Anat & Physiol, DK-1870 Frederiksberg C, Denmark

来源：

REPRODUCTION IN DOMESTIC ANIMALS | 2000年 / 35卷 / 3-4期

关键词：

D O I：

暂无

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Renin, angiotensin converting enzyme, and angiotensin II receptors are expressed in the bovine utero-placental unit, indicating the presence of a local renin-angiotensin system (RAS). Angiotensin II receptors of type AT(1) and AT(2) as well as non-AT(1)/non-AT(2) binding sites were identified. The expression of both renin and the angiotensin II receptor types in the bovine utero-placental unit differs from that in humans. This fact is probably related to differences in placental architecture. The RAS in the bovine utero-placental unit might be important for growth processes in the endometrium and for placentation. It might also participate in the regulation of the utero-placental blood flow and secretion of hormones. Disturbances in the utero-placental RAS might cause a reduced utero-placental blood flow, intrauterine growth retardation and intrauterine death.

引用

页码：153 / 156

页数：4

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