Antihyperglycemic and Antihyperlipidemic Activity of Hydroponic Stevia rebaudiana Aqueous Extract in Hyperglycemia Induced by Immobilization Stress in Rabbits

被引：16
作者：
Aghajanyan, Anush [1 ,2 ]
Movsisyan, Zaruhi [1 ]
Trchounian, Armen [1 ,2 ]
机构：
[1] Yerevan State Univ, Dept Biochem Microbiol & Biotechnol, Fac Biol, Yerevan 0025, Armenia
[2] Yerevan State Univ, Res Inst Biol, Fac Biol, Yerevan 0025, Armenia
来源：
BIOMED RESEARCH INTERNATIONAL | 2017年 / 2017卷
关键词：
BLOOD-GLUCOSE; INSULIN SENSITIVITY; STEVIOSIDE; LEAVES; CHOLESTEROL; MECHANISM; BERTONI; PLASMA;
D O I：
10.1155/2017/9251358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Diabetes mellitus (DM) is a serious worldwide problem related to human hyperglycemia. Thus, herbal preparations with antihyperglycemic properties especially leaf extracts of hydroponic Stevia rebaudiana (SR) would be useful in hyperglycemia treatment. The antihyperglycemic potential of this medicinal plant grown using hydroponics methods has been evaluated. Significant reduction of some biochemical characteristics for sugars and fatty acids in blood, liver, and muscle especially fasting glucose levels, serum triglycerides, LDL-cholesterol, total cholesterol levels, and increased HDL-cholesterol ones was shown with SR aqueous extract treatment. Therefore, the aqueous extract of SR is suggested to have antihyperglycemic and antihyperlipidemic activity and to restore liver and muscle glycogen levels (hepatoprotective effects) in hyperglycemia induced by immobilization stress in rabbits and might be recommended for treatment of DM (hyperglycemia).
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页数：6
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