A practical Δ1-dehydrogenation of Δ4-3-keto-steroids with DDQ in the presence of TBDMSCl at room temperature

被引：41

作者：

Chen, Kaixiong ^{[1
]}

Liu, Chang ^{[1
]}

Deng, Le ^{[1
]}

Xu, Guangyu ^{[1
]}

机构：

[1] Hunan Normal Univ, Coll Chem & Chem Engn, Changsha 410081, Hunan, Peoples R China

来源：

STEROIDS | 2010年 / 75卷 / 07期

关键词：

Delta(1)-Dehydrogenation; Delta(4)-3-Ketosteroid; DDQ; Chlorosilane; SILYL ENOL ETHERS; SUBSTRATE ADDUCTS; OXIDATION; CONVERSION;

D O I：

10.1016/j.steroids.2010.03.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A mild and efficient Delta(1)-dehydrogenation of Delta(4)-3-keto-steroids with DDQ in the presence of tert-butyldimethylchlorosilane at room temperature was developed. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：513 / 516

页数：4

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