Clinical Efficacy of Qizhi Yifei Granules on Patients with High Peripheral Blood Eosinophil-Type Acute Exacerbation of Chronic Obstructive Pulmonary Disease

被引:2
作者
Liu, Hongxiang [1 ]
Li, Yifan [1 ]
Zhang, Xiaoying [2 ]
Shi, Man [3 ]
Meng, Xiaomin [1 ]
Li, Dexu [1 ]
机构
[1] Hebei Univ, Dept Integrated Tradit Chinese & Western Med, Affiliated Hosp, 212 Yuhua East Rd, Baoding 071000, Heibei, Peoples R China
[2] Hebei Univ, Res Student Acad, Baoding 071000, Heibei, Peoples R China
[3] Hebei Univ, Dept Cardiovasc Med, Affiliated Hosp, Baoding 071000, Heibei, Peoples R China
关键词
Clinical efficacy; High peripheral blood eosinophil-type AECOPD; IL-17; 1L-8; Qizhi Yifei granules; TNF-alpha; RESPIRATORY SYMPTOMS; COPD; INFLAMMATION; AECOPD; PRINCIPLES; THERAPY; RISK;
D O I
10.37290/ctnr2641-452X.20:298-305
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
We have examined the clinical efficacy of Qizhi Yifei granules on patients with high peripheral blood eosinophil-type acute exacerbation of chronic obstructive pulmonary disease and its effect on serum interleukin-8, interleukin-17, and tumor necrosis factor-alpha levels. A total of 80 patients were enrolled and assigned to the control p (n = 36) and treatment groups (n = 44) . Patients in the control group received conventional symptomatic treatment, while patients in the treatment group received additional Qizhi Yifei granules based on treatment for the control group. Treatment with Qizhi Yifei granules resulted in early diminution of clinical symptoms; higher acidity levels; lower levels of interleukin-8, interleukin-17, and tumor necrosis factor-alpha; and lower eosinophil count. In addition, the treatment group showed a lower score on disease assessment and higher clinical efficacy than the control group. The incidence of adverse reactions after intervention was not greatly different between the two groups. In conclusion, for patients with high peripheral blood eosinophil-type acute exacerbation of chronic obstructive pulmonary disease, treatment with Qizhi Yifei granules can lower their eosinophil count, alleviate clinical symptoms, and lower inflammatory factors, thus delivering higher clinical efficacy.
引用
收藏
页码:298 / 305
页数:8
相关论文
共 50 条
  • [1] Peripheral Blood Eosinophil as a Biomarker in Outcomes of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Wu, Hong-Xia
    Zhuo, Kai-Quan
    Cheng, De-Yun
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2019, 14 : 3003 - 3015
  • [2] Blood Eosinophil Levels and Prognosis of Hospitalized Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Yu, Songsong
    Zhang, Jie
    Fang, Qiuhong
    Tong, Zhaohui
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2021, 362 (01) : 56 - 62
  • [3] Blood Eosinophil Count and Hospital Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Hegewald, Matthew J.
    Horne, Benjamin D.
    Trudo, Frank
    Kreindler, James L.
    Chung, Yen
    Rea, Susan
    Blagev, Denitza P.
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2020, 15 : 2629 - 2641
  • [4] Apoptosis of T Lymphocytes Isolated from Peripheral Blood of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Lim, Sung Chul
    Ju, Jin Yung
    Chi, Su Young
    Ban, Hee Jung
    Kwon, Yong Soo
    Oh, In Jae
    Kim, Kyu Sik
    Kim, Yu Il
    Kim, Young Chul
    YONSEI MEDICAL JOURNAL, 2011, 52 (04) : 581 - 587
  • [5] Pulmonary Embolism in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Cao, Yao-Qian
    Dong, Li-Xia
    Cao, Jie
    CHINESE MEDICAL JOURNAL, 2018, 131 (14) : 1732 - 1737
  • [6] Peripheral blood eosinophil count as a biomarker of exacerbation in stable chronic obstructive pulmonary disease outpatients: a prospective observational study
    Safwat, Tarek
    El-Sheikh, Mohammed
    El-Sayed, Amira
    Abd-Elsattar, Dalia
    EGYPTIAN JOURNAL OF CHEST DISEASES AND TUBERCULOSIS, 2023, 72 (03): : 313 - 319
  • [7] Prevalence and clinical characteristics of blood eosinophilia in patients with acute exacerbation of chronic obstructive pulmonary disease
    曾强林
    ChinaMedicalAbstracts(InternalMedicine), 2017, 34 (04) : 219 - 219
  • [8] Immunodeficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Xie, Sheling
    Wang, Kaifei
    Zhang, Wei
    Xiao, Kun
    Yan, Peng
    Li, Yanqin
    He, Wanxue
    Zhang, Yuhan
    Xie, Lixin
    INFLAMMATION, 2018, 41 (05) : 1582 - 1589
  • [9] Blood Eosinophil and Risk of Exacerbation in Chronic Obstructive Pulmonary Disease Patients: A Retrospective Cohort Analysis
    Chan, Ming Chiu
    Yeung, Yiu Cheong
    Yu, Ellen Lok Man
    Yu, Wai Cho
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2020, 15 : 2869 - 2877
  • [10] Clinical Characteristics of Overweight Patients With Acute Exacerbation Chronic Obstructive Pulmonary Disease (AECOPD)
    Gong, Yuxin
    Du, Fawang
    Yao, Yu
    Wang, Hanchao
    Wang, Xiaochuan
    Xiong, Wei
    Wang, Qin
    He, Gaoyan
    Chen, Linlin
    Du, Heng
    Yang, Juan
    Bauer, Brent A.
    Wang, Zhongruo
    Deng, Huojin
    Zhu, Tao
    CLINICAL RESPIRATORY JOURNAL, 2024, 18 (08)