The evaluation of reno- and hepato-protective effects of Huai-Shan-Yao (Rhizome Dioscoreae)

被引：21
作者：
Lee, SC
Tsai, CC
Chen, JC
Lin, CC
Hu, ML
Lu, S [1 ]
机构：
[1] Natl Chung Hsing Univ, Dept Food Sci, Taichung 40227, Taiwan
[2] China Med Coll, Sch Postbaccalaureate Chinese Med, Taipei, Taiwan
[3] China Med Coll, Sch Chinese Med, Taipei, Taiwan
[4] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung, Taiwan
来源：
AMERICAN JOURNAL OF CHINESE MEDICINE | 2002年 / 30卷 / 04期
关键词：
Huai-Shan-Yao; protective effects; kidney; liver;
D O I：
10.1142/S0192415X02000624
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Huai-Shan-Yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of Huai-Shan-Yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of Huai-Shan-Yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.
引用
收藏
页码：609 / 616
页数：8
相关论文
共 15 条
[1]   Genetic polymorphisms of alcohol metabolizing enzymes [J].
Agarwal, DP .
PATHOLOGIE BIOLOGIE, 2001, 49 (09) :703-709
[2]  
[Anonymous], 1996, CASARETT DOULLS TOXI
[3]  
Araghinikam Mohsen, 1996, Life Sciences, V59, P147
[4]  
*GEN HLTH STAT, 2002, 10 LEAD CAUS DEATH T
[5]   Zulu medicinal plants with antibacterial activity [J].
Kelmanson, JE ;
Jäger, AK ;
van Staden, J .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 69 (03) :241-246
[6]  
KOCH HP, 1985, METHOD FIND EXP CLIN, V7, P13
[7]   FORMATION OF THE 37KD PROTEIN-ACETALDEHYDE ADDUCT IN LIVER DURING ALCOHOL TREATMENT IS DEPENDENT ON ALCOHOL-DEHYDROGENASE ACTIVITY [J].
LIN, RC ;
LUMENG, L .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1990, 14 (05) :766-770
[8]  
LU FC, 1996, BASIC TOXICOLOGY FUN, P191
[9]   TRADITIONAL MANAGEMENT OF LIVER DISORDERS [J].
MESSNER, M ;
BRISSOT, P .
DRUGS, 1990, 40 :45-57
[10]  
Ou M, 1988, REGULAR CHINESE MED
12