Synthesis and characterization of binary and ternary oxovanadium complexes of N,N′-(2-pyridyl)thiourea and curcumin: Catalytic oxidation potential, antibacterial, antimicrobial, antioxidant and DNA interaction studies

被引：34

作者：

Adam, Mohamed Shaker S. ^{[1
,2
]}

Youssef, Magdy M. ^{[1
,3
]}

Aboelghar, Maha F. ^{[1
,4
]}

Hafez, Aly M. ^{[1
]}

El-Ayaan, Usama ^{[1
,3
]}

机构：

[1] King Faisal Univ, Coll Sci, Dept Chem, POB 380, Al Hufuf 31982, Al Hassa, Saudi Arabia

[2] Sohag Univ, Fac Sci, Dept Chem, Sohag 82534, Egypt

[3] Mansoura Univ, Fac Sci, Chem Dept, Mansoura 35516, Egypt

[4] Cairo Univ, Fac Sci, Chem Dept, Giza, Egypt

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2017年 / 31卷 / 07期

关键词：

1-octene; antibacterial; antimicrobial; antioxidant; catalytic oxidation; curcumin; DNA; oxovanadium (IV); pyridylthiourea; AQUEOUS HYDROGEN-PEROXIDE; SCHIFF-BASE LIGANDS; TEMPERATURE;

D O I：

10.1002/aoc.3650

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two binary and two ternary mono-oxovanadium (IV) complexes of acetylacetonate, curcumin and N,N'-bis(2-pyridyl)thiourea were synthesized. They were characterized using elemental analysis, infrared and UV-visible spectroscopies and magnetic and conductivity measurements. The formation constants K-f were determined from spectrophotometric measurements. The catalytic potential of the VO complexes was investigated for the oxidation of 1-octene by aqueous H2O2 in acetonitrile. They display high catalytic potential for the conversion of 1-octene with low chemoselectivity to the epoxy product. The VO complexes exhibit good antibacterial and antimicrobial activities. The antioxidant activity of the VO complexes and their ligands was investigated. The VO complexes show high DNA affinity and DNA cleavage ability.

引用

页数：10

共 44 条

[1] Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes [J].

Abdel-Rahman, Laila H. ;

El-Khatib, Rafat M. ;

Nassr, Lobna A. E. ;

Abu-Dief, Ahmed M. .

JOURNAL OF MOLECULAR STRUCTURE, 2013, 1040 :9-18

[2]

[Anonymous], POLYHEDRON

[3] Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats [J].

Arun, N ;

Nalini, N .

PLANT FOODS FOR HUMAN NUTRITION, 2002, 57 (01) :41-52

[4] Synthesis of symmetric N,O-donor ligands derived from pyridoxal (vitamin B6): DFT studies and structural features of their binuclear chelate complexes with the oxofilic uranyl and vanadyl(V) cations [J].

Back, Davi Fernando ;

de Oliveira, Gelson Manzoni ;

Roman, Daiane ;

Ballin, Marco Aurelio ;

Kober, Roger ;

Piquini, Paulo Cesar .

INORGANICA CHIMICA ACTA, 2014, 412 :6-14

[5] Photoactivated cytotoxicity of ferrocenyl-terpyridine oxovanadium(IV) complexes of curcuminoids [J].

Balaji, Babu ;

Balakrishnan, Babita ;

Perumalla, Sravanakumar ;

Karande, Anjali A. ;

Chakravarty, Akhil R. .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 85 :458-467

[6] Chiral vanadyl salen complex anchored on supports as recoverable catalysts for the enantioselective cyanosilylation of aldehydes.: Comparison among silica, single wall carbon nanotube, activated carbon and imidazolium ion as support [J].

Baleizao, C ;

Gigante, B ;

García, H ;

Corma, A .

TETRAHEDRON, 2004, 60 (46) :10461-10468

[7] Oxovanadium(IV) complexes of curcumin for cellular imaging and mitochondria targeted photocytotoxicity [J].

Banik, Bhabatosh ;

Somyajit, Kumar ;

Nagaraju, Ganesh ;

Chakravarty, Akhil R. .

DALTON TRANSACTIONS, 2014, 43 (35) :13358-13369

[8]

BAUER AW, 1966, AM J CLIN PATHOL, V45, P493

[9] DISTRIBUTION OF IRON-CONTAINING SUPEROXIDE-DISMUTASE IN VASCULAR PLANTS [J].

BRIDGES, SM ;

SALIN, ML .

PLANT PHYSIOLOGY, 1981, 68 (02) :275-278

[10]

Chopra R.N., 1958, INDIGENOUS DRUGS IND, Vsecond

← 1 2 3 4 5 →