Synthesis, Characterisation and Antimicrobial Activities of Copper(II) and Zinc(II) Complexes of Schiff Bases derived from Amino Acids and 1,10-Phenanthroline Mixed Ligands

被引：0

作者：

Ndifon, Peter T.

Moise, Agwara O. ^{[2
]}

Julius, Njapba N.

Mbom, Yufenyi D. ^{[1
]}

Awawou, Paboudam G.

Lynda, Nyamen D. ^{[2
]}

机构：

[1] Univ Buea, Dept Chem, Buea, Cameroon

[2] Univ Yaounde 1, Fac Sci, Dept Inorgan Chem, Coordinat Chem Lab, Yaounde, Cameroon

来源：

RESEARCH JOURNAL OF CHEMISTRY AND ENVIRONMENT | 2010年 / 14卷 / 02期

关键词：

Schiff bases; 1,10-phenanthroline; copper(II); zinc(II); antimicrobial activities; BIOLOGICAL-PROPERTIES; CRYSTAL-STRUCTURES; METAL-COMPLEXES; OXOVANADIUM(IV); CU(II);

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper(II) and Zinc(II) complexes of Schiff bases and 1,10-phenanthroline mixed ligands have been synthesized in aqueous/methanolic solution. These complexes were characterised by elemental analyses, infrared and visible electronic spectroscopy. The results suggest a distorted octahedral coordination for Cu(II) and Zn(II) complexes in which the central metal ion is bonded to O-, N- and O- donor sites of the imino-N, phenoxyl-O and carboxyl-O groups respectively. Antimicrobial studies on the ligands and the metal complexes show that the ligands, salicylidene alanine (Sal-Al) and salicylidene histidine(Sal-His) are active against 3 out of the 8 tested organisms while the copper complex Cu(Sal-Ala)phen is active against 4 of the pathogens. The zinc complex Zn(Sal-Ala)phen is active against 7 of the pathogens. None of them is active against the fungus, candida albicans.

引用

页码：50 / 54

页数：5

共 23 条

[1] Bimetallic complexes of Schiff base bis-[4-hydroxycuomarin-3-yl]-1N,5N-thiocarbohydrazone as a potentially dibasic pentadentate ligand.: Synthesis, spectral, and antimicrobial properties
Abou-Melha, K. S.
Faruk, H.
[J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2008, 5 (01) : 122 - 134
[2] Bonghaei D. M., 2007, SPECTROCHIM ACTA A, V67, P944
[3] COORDINATION MODES OF HISTIDINE .2. STEREOCHEMISTRY OF THE REACTION BETWEEN HISTIDINE DERIVATIVES AND PYRIDOXAL ANALOGS - CONFORMATIONAL PROPERTIES OF ZINC(II) COMPLEXES OF HISTIDINE SCHIFF-BASES
CASELLA, L
GULLOTTI, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (21) : 6338 - 6347
[4] N-SALICYLIDENEAMINO ACIDATE COMPLEXES OF OXOVANADIUM(IV) .1. CRYSTAL AND MOLECULAR-STRUCTURES AND SPECTROSCOPIC PROPERTIES
CAVACO, I
PESSOA, JC
COSTA, D
DUARTE, MT
GILLARD, RD
MATIAS, P
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1994, (02): : 149 - 157
[5] CHIHUEY W, 2003, PURE APPL CHEM, V75, P179
[6] Resistance mechanisms of bacteria to antimicrobial compounds
Cloete, TE
[J]. INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 2003, 51 (04) : 277 - 282
[7] Crystal structures of the N-salicylidene-L-serinatoaquacopper(II) monohydrate and its ternary derivative with 2-aminopyridine
García-Raso, A
Fiol, JJ
López-Zafra, A
Cabrero, A
Mata, I
Molins, E
[J]. POLYHEDRON, 1999, 18 (06) : 871 - 878
[8] Synthesis of ZnN-salicylidene-L-aminoacidatos:: X-ray structure of [(N-salicylidene-L-alaninato) (aqua)zinc(II)]•0.25H2O and [(N-salicylidene-L-valinato) (aqua)zinc(II)]
García-Raso, A
Fiol, JJ
López-Zafra, A
Mata, I
Espinosa, E
Molins, E
[J]. POLYHEDRON, 2000, 19 (06) : 673 - 680
[9] Cd(II) and Cu(II) complexes of polydentate Schiff base ligands: synthesis, characterization, properties and biological activity
Golcu, A
Tumer, M
Demirelli, H
Wheatley, RA
[J]. INORGANICA CHIMICA ACTA, 2005, 358 (06) : 1785 - 1797
[10] Iqbal Javed, 2006, Turkish Journal of Biology, V30, P1

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