Synthesis, Characterisation and Antimicrobial Activities of Copper(II) and Zinc(II) Complexes of Schiff Bases derived from Amino Acids and 1,10-Phenanthroline Mixed Ligands

被引：0

作者：

Ndifon, Peter T.

Moise, Agwara O. ^{[2
]}

Julius, Njapba N.

Mbom, Yufenyi D. ^{[1
]}

Awawou, Paboudam G.

Lynda, Nyamen D. ^{[2
]}

机构：

[1] Univ Buea, Dept Chem, Buea, Cameroon

[2] Univ Yaounde 1, Fac Sci, Dept Inorgan Chem, Coordinat Chem Lab, Yaounde, Cameroon

来源：

RESEARCH JOURNAL OF CHEMISTRY AND ENVIRONMENT | 2010年 / 14卷 / 02期

关键词：

Schiff bases; 1,10-phenanthroline; copper(II); zinc(II); antimicrobial activities; BIOLOGICAL-PROPERTIES; CRYSTAL-STRUCTURES; METAL-COMPLEXES; OXOVANADIUM(IV); CU(II);

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper(II) and Zinc(II) complexes of Schiff bases and 1,10-phenanthroline mixed ligands have been synthesized in aqueous/methanolic solution. These complexes were characterised by elemental analyses, infrared and visible electronic spectroscopy. The results suggest a distorted octahedral coordination for Cu(II) and Zn(II) complexes in which the central metal ion is bonded to O-, N- and O- donor sites of the imino-N, phenoxyl-O and carboxyl-O groups respectively. Antimicrobial studies on the ligands and the metal complexes show that the ligands, salicylidene alanine (Sal-Al) and salicylidene histidine(Sal-His) are active against 3 out of the 8 tested organisms while the copper complex Cu(Sal-Ala)phen is active against 4 of the pathogens. The zinc complex Zn(Sal-Ala)phen is active against 7 of the pathogens. None of them is active against the fungus, candida albicans.

引用

页码：50 / 54

页数：5

共 23 条

[1] Bimetallic complexes of Schiff base bis-[4-hydroxycuomarin-3-yl]-1N,5N-thiocarbohydrazone as a potentially dibasic pentadentate ligand.: Synthesis, spectral, and antimicrobial properties [J].