CDK1/CYCLIN B1 MEDIATED BCL-XL/BCL-2 PHOSPHORYLATION PRO-APOPTOTIC SIGNAL FOLLOWING MITOTIC ARREST AND MICROTUBLE INHIBITOR TREATMENT

被引:0
|
作者
Terrano, D. [1 ]
Joheim, J. J. [1 ]
Sakurikar, N. [1 ]
Makhoul, I. [1 ]
Hutchins, L. F. [1 ]
Chambers, T. C. [1 ]
机构
[1] Univ Arkansas Med Sci, Little Rock, AR 72205 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
74
引用
收藏
页码:666 / 666
页数:1
相关论文
共 40 条
  • [1] Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-XL phosphorylation
    Choi, Hye Joung
    Zhu, Bao Ting
    STEROIDS, 2019, 150
  • [2] CDK1-mediated phosphorylation and inactivation of Bcl-xL/Bcl-2: A functional link between mitotic arrest and apoptosis
    Terrano, David
    Chambers, Timothy
    CANCER RESEARCH, 2009, 69
  • [3] Role of Cyclin B1/Cdc2 in Mediating Bcl-XL Phosphorylation and Apoptotic Cell Death Following Nocodazole-Induced Mitotic Arrest
    Choi, Hye Joung
    Zhu, Bao Ting
    MOLECULAR CARCINOGENESIS, 2014, 53 (02) : 125 - 137
  • [4] Inhibition of Notch enhances pro-apoptotic effect of Bcl-2/Bcl-xL inhibitor in multiple myeloma
    Nefedova, Yulia
    Clifton, Nickolas
    Dalton, William
    Gabrilovich, Dmitry
    CANCER RESEARCH, 2009, 69
  • [5] Cyclin-Dependent Kinase 1-Mediated Bcl-xL/Bcl-2 Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis
    Terrano, David T.
    Upreti, Meenakshi
    Chambers, Timothy C.
    MOLECULAR AND CELLULAR BIOLOGY, 2010, 30 (03) : 640 - 656
  • [6] Cyclin-dependent Kinase-1 (Cdk1)/Cyclin B1 Dictates Cell Fate after Mitotic Arrest via Phosphoregulation of Antiapoptotic Bcl-2 Proteins
    Sakurikar, Nandini
    Eichhorn, Joshua M.
    Chambers, Timothy C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (46) : 39193 - 39204
  • [7] Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak
    J Megyesi
    A Tarcsafalvi
    NSHL Seng
    R Hodeify
    PM Price
    Cell Death Discovery, 2
  • [8] Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak
    Megyesi, J.
    Tarcsafalvi, A.
    Seng, N. S. H. L.
    Hodeify, R.
    Price, P. M.
    CELL DEATH DISCOVERY, 2016, 2
  • [9] Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-xL
    Hausmann, G
    O'Reilly, LA
    van Driel, R
    Beaumont, JC
    Strasser, A
    Adams, JM
    Huang, DCS
    JOURNAL OF CELL BIOLOGY, 2000, 149 (03): : 623 - 633
  • [10] CDK1 switches mitotic arrest to apoptosis by phosphorylating Bcl-2/Bax family proteins during treatment with microtubule interfering agents
    Zhou, Lingli
    Cai, Xiaoling
    Han, Xueyao
    Xu, Naihan
    Chang, Donald C.
    CELL BIOLOGY INTERNATIONAL, 2014, 38 (06) : 737 - 746