Differentiation Epitopes Define Hematopoietic Stem Cells and Change with Cell Cycle Passage

被引：3
作者：
Goldberg, Laura R. [1 ]
Dooner, Mark S. [1 ]
Papa, Elaine [1 ]
Pereira, Mandy [1 ]
Del Tatto, Michael [1 ]
Cheng, Yan [1 ]
Wen, Sicheng [1 ]
Quesenberry, Peter J. [1 ]
机构：
[1] Brown Univ, Rhode Isl Hosp, Div Hematol Oncol, 1 Hoppin St,Coro West Bldg Suite 5-01, Providence, RI 02903 USA
来源：
STEM CELL REVIEWS AND REPORTS | 2022年 / 18卷 / 07期
关键词：
Hematopoietic stem cells; Lineage positive cells; Stem cell purification; Cell cycle; Differentiation; LONG-TERM; GENE-EXPRESSION; CLONAL ANALYSIS; PROGENITORS; HETEROGENEITY; REVEALS; FATE; IDENTIFICATION; COMMITMENT; HIERARCHY;
D O I：
10.1007/s12015-022-10374-4
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Hematopoietic stem cells express differentiation markers B220 and Gr1 and are proliferative. We have shown that the expression of these entities changes with cell cycle passage. Overall, we conclude that primitive hematopoietic stem cells alter their differentiation potential with cell cycle progression.
引用
收藏
页码：2351 / 2364
页数：14
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