Novel aza-BODIPY based small molecular NIR-II fluorophores for in vivo imaging

被引：146

作者：

Bai, Lei ^{[1
,2
]}

Sun, Pengfei ^{[3
,4
]}

Liu, Yi ^{[1
,2
]}

Zhang, Hang ^{[1
,2
]}

Hu, Wenbo ^{[1
,2
]}

Zhang, Wansu ^{[3
,4
]}

Liu, Zhipeng ^{[1
,2
]}

Fan, Quli ^{[3
,4
]}

Li, Lin ^{[1
,2
]}

Huang, Wei ^{[1
,2
,3
,4
,5
]}

机构：

[1] Nanjing Tech Univ NanjingTech, Key Lab Flexible Elect KLOFE, Nanjing 211816, Jiangsu, Peoples R China

[2] Nanjing Tech Univ NanjingTech, IAM, Nanjing 211816, Jiangsu, Peoples R China

[3] Nanjing Univ Posts & Telecommun, Key Lab Organ Elect & Informat Displays, Nanjing 210023, Jiangsu, Peoples R China

[4] Nanjing Univ Posts & Telecommun, IAM, Nanjing 210023, Jiangsu, Peoples R China

[5] Northwestern Polytech Univ, SIFE, 127 West Youyi Rd, Xian 710072, Shaanxi, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 73期

基金：

中国国家自然科学基金;

关键词：

WALLED CARBON NANOTUBES; QUANTUM DOTS; HIGHLY FLUORESCENT; BRIGHT; DYE;

D O I：

10.1039/c9cc03378e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of new NIR-II fluorophores, particularly those with facile syntheses, high fluorescence quantum yields, and stable and tunable photophysical properties, is challenging. Herein, we report a new class of small molecular NIR-II fluorophores based on aza-dipyrromethene boron difluoride (aza-BODIPY) dyes. We demonstrate promising photophysical properties of these dyes, such as large Stokes shift, superior photostability, and good fluorescence brightness as nanoparticles in aqueous solution. Because of these properties and high resolution and deep penetration NIR-II imaging ability, the aza-BODIPY based dyes show great potential as NIR-II imaging agents.

引用

页码：10920 / 10923

页数：4

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