One-Pot, Pseudo Four-Component Synthesis of a Spiro[diindeno[1,2-b:2′,1′-e]pyridine-11,3′-indoline]-trione Library

被引:85
作者
Ghahremanzadeh, Ramin [1 ]
Shakibaei, Ghazaleh Imani [1 ]
Ahadi, Somayeh [1 ]
Bazgir, Ayoob [1 ]
机构
[1] Shaheed Beheshti Univ, Dept Chem, GC, Tehran, Iran
来源
JOURNAL OF COMBINATORIAL CHEMISTRY | 2010年 / 12卷 / 01期
关键词
3-COMPONENT SYNTHESIS; EFFICIENT SYNTHESIS; DERIVATIVES; ISATINS; SPIROOXINDOLES; HETEROCYCLES; INHIBITORS; ACID;
D O I
10.1021/cc900130a
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A one-pot, pseudo four-component method for the efficient and simple synthesis of spiro[diindeno[1,2-b: 2',1'-e]pyridine-11,3'-indoline]-2',10,12-trione derivatives in refluxing acetonitrile is reported. The features of this procedure are mild reaction conditions, high yields of products, and operational simplicity.
引用
收藏
页码:191 / 194
页数:4
相关论文
共 50 条
[1]   Synthesis and evaluation of some new spiro indoline-based heterocycles as potentially active antimicrobial agents [J].
Abdel-Rahman, AH ;
Keshk, EM ;
Hanna, MA ;
El-Bady, SM .
BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (09) :2483-2488
[2]   A clean synthesis of spiro[indoline-3,9′-xanthene]trione derivatives [J].
Ahadi, Somayeh ;
Khavasi, Hamid Reza ;
Bazgir, Ayoob .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 56 (09) :1328-1330
[3]   An efficient synthesis of spiro[dibenzo[b,i]xanthene-13,3′-indoline]-pentaones and 5H-dibenzo[b,i]xanthene-tetraones [J].
Bazgir, Ayoob ;
Tisseh, Zeinab Noroozi ;
Mirzaei, Peiman .
TETRAHEDRON LETTERS, 2008, 49 (35) :5165-5168
[4]   A novel three-component method for the synthesis of triazolo[1,2-a]indazole-triones [J].
Bazgir, Ayoob ;
Seyyedhamzeh, Mozhdeh ;
Yasaei, Zahra ;
Mirzaei, Peiman .
TETRAHEDRON LETTERS, 2007, 48 (50) :8790-8794
[5]   A novel metal iodide promoted three-component synthesis of substituted pyrrolidines [J].
Bertozzi, F ;
Gustafsson, M ;
Olsson, R .
ORGANIC LETTERS, 2002, 4 (18) :3147-3150
[6]  
Bienaymé H, 2000, CHEM-EUR J, V6, P3321, DOI 10.1002/1521-3765(20000915)6:18<3321::AID-CHEM3321>3.0.CO
[7]  
2-A
[8]  
Brandes A., 1998, J. -Schuhmacher, Ger. Offen., Patent No. [DE 19627430 A1 19980115, 19627430, 19627430 A1 19980115]
[9]   A convenient solution and solid-phase synthesis of Δ5-2-oxopiperazines via N-acyliminium ions cyclization [J].
Cheng, JF ;
Chen, M ;
Arrhenius, T ;
Nadzan, A .
TETRAHEDRON LETTERS, 2002, 43 (36) :6293-6295
[10]  
Cooper K, 1989, Eur Pat Appl, Patent No. [299727, EP 299727 A1 19890118]