Molecular identification of cystic echinococcosis in humans and pigs reveals the presence of both Echinococcus granulosus sensu stricto and Echinococcus canadensis G6/G7 in the hyperendemic focus of the Republic of Moldova

被引：3

作者：

Umhang, Gerald ^{[1
]}

Chihai, Oleg ^{[2
]}

Bastid, Vanessa ^{[1
]}

Grenouillet, Florence Elisabeth ^{[3
,4
,5
]}

Erhan, Dumitru ^{[2
]}

Hotineanu, Adrian ^{[6
]}

Lungu, Vera ^{[7
]}

Rusu, Stefan ^{[2
]}

Grenouillet, Frederic ^{[3
,4
,5
]}

Boue, Franck ^{[1
]}

机构：

[1] ANSES, Nancy Lab Rabies & Wildlife, Natl Reference Lab Echinococcus Spp, Wildlife Surveillance & Ecoepidemiol Unit, Technopole Agr & Vet 40009, F-54220 Malzeville, France

[2] Moldavian Acad Sci, Inst Zool, Kishinev, Moldova

[3] French Natl Reference Ctr Alveolar Echinococcosis, Parasite & Fungal Serol Unit, Besancon, France

[4] WHO Collaborating Ctr Prevent & Treatment Human E, Univ Hosp, Besancon, France

[5] Univ Bourgogne Franche Comte, Chronoenvironm, UMR UFC CNRS Aff INRA 6249, Besancon, France

[6] Republican Clin Hosp Timofei Mosneaga, Hepatobiliopancreat Dept, Kishinev, Moldova

[7] Natl Ctr Publ Hlth, Parasit Surveillance Div, Kishinev, Moldova

来源：

PARASITOLOGY RESEARCH | 2019年 / 118卷 / 10期

关键词：

Echinococcus granulosus sensu stricto; Echinococcus canadensis G6; G7; Cystic echinococcosis; Human; Pig; G7; EPIDEMIOLOGY; PREVALENCE; GENOTYPE; CATTLE; STRAIN; SPP;

D O I：

10.1007/s00436-019-06432-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Cystic echinococcosis is caused by the parasitic species of the complex Echinococcus granulosus sensu lato. This disease is hyperendemic in the Republic of Moldova. Recent molecular analyses have revealed the exclusive presence of E. granulosus sensu stricto in sheep and cattle. Previous reports of prevalence in pigs suggest the potential presence of Echinococcus canadensis G6/G7, as this species is also reported in neighboring countries. The presence of cystic echinococcosis in pigs was specifically monitored at the slaughterhouse. In the meantime, human cases were genotyped for the first time. E. canadensis G6/G7 was identified in all ten pigs infected by E. granulosus s.l. One human case of infection by E. canadensis G6/G7 was also identified, while E. granulosus sensu stricto was found to be the cause for the 13 others. The description of one human case of E. canadensis G6/G7 has confirmed its zoonotic impact in the country. Future studies will be needed to estimate the relative proportion and distribution of both parasitic species in Moldova.

引用

页码：2857 / 2861

页数：5

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