New laboratory markers for the management of rheumatoid arthritis patients

被引：3

作者：

Foti, Daniela P. ^{[2
]}

Greco, Marta ^{[2
]}

Palella, Eleonora ^{[2
]}

Gulletta, Elio ^{[1
]}

机构：

[1] Dept Hlth Sci, I-88100 Catanzaro, Italy

[2] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Clin Pathol Unit, Catanzaro, Italy

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2014年 / 52卷 / 12期

关键词：

evidence-based laboratory medicine (EBLM); immunopathogenesis; laboratory assay; rheumatoid arthritis; NATURAL-KILLER-CELLS; PROTEOMIC ANALYSIS; AUTOIMMUNE; PATHOGENESIS; CYTOKINES; CLASSIFICATION; ASSOCIATION; CHEMOKINES; ANTIBODIES; PROTEINS;

D O I：

10.1515/cclm-2014-0383

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Rheumatoid arthritis, the most prominent of systemic autoimmune rheumatic diseases, represents an important social health problem. Recent insights into the immunopathogenic mechanism of this complex and multiform illness might open new perspectives for a more appropriate laboratory approach. In this review we focus on the most relevant pathogenetic mechanism; indicating the laboratory biomarkers specifically linked to early diagnosis, prognosis, evolutive aspects of the disease, and therapeutic efficacy. Evidence based on laboratory medicine could provide the best outcome for patients.

引用

页码：1729 / 1737

页数：9

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