Effect of the Procalcitonin Assay on Antibiotic Use in Critically Ill Children

被引:6
作者
Ross, Rachael K. [1 ]
Keele, Luke [2 ]
Kubis, Sherri [3 ]
Lautz, Andrew J. [4 ]
Dziorny, Adam C. [5 ]
Denson, Adam R. [5 ]
O'Connor, Kathleen A. [5 ]
Chilutti, Marianne R. [6 ]
Weiss, Scott L. [5 ]
Gerber, Jeffrey S. [1 ,7 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Infect Dis,Dept Pediat, Philadelphia, PA 19104 USA
[2] Georgetown Univ, McCourt Sch Publ Policy, Washington, DC USA
[3] Childrens Hosp Philadelphia, Dept Nursing Resp Care & Neurodiagnost Serv, Philadelphia, PA 19104 USA
[4] Cincinnati Childrens Hosp Med Ctr, Dept Pediat, Div Crit Care Med, Cincinnati, OH 45229 USA
[5] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Crit Care Med,Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA
[6] Childrens Hosp Philadelphia, Dept Biomed & Hlth Informat, Philadelphia, PA 19104 USA
[7] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Gen Pediat,Dept Pediat, Philadelphia, PA 19104 USA
关键词
antibiotics; critical care; pediatric; procalcitonin; RANDOMIZED CONTROLLED-TRIAL; BIAS REDUCTION; MULTICENTER; SEPSIS; SENSITIVITY; INFECTIONS; THERAPY; IMPACT;
D O I
10.1093/jpids/piy004
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We retrospectively studied the effect of introducing procalcitonin into clinical practice on antibiotic use within a large academic pediatric intensive care unit. In the absence of a standardized algorithm, availability of the procalcitonin assay did not reduce the frequency of antibiotic initiations or the continuation of antibiotics for greater than 72 hours.
引用
收藏
页码:E43 / E46
页数:4
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