The Role of Margins in Extremity Soft Tissue Sarcoma

被引：46

作者：

Byerly, Saskya ^{[1
]}

Chopra, Shefali ^{[1
]}

Nassif, Nader A. ^{[2
]}

Chen, Peter ^{[2
]}

Sener, Stephen F. ^{[1
]}

Eisenberg, Burton L. ^{[2
]}

Tseng, William W. ^{[1
,2
]}

机构：

[1] Univ So Calif, Keck Sch Med, Dept Surg, Sect Surg Oncol, 1510 San Pablo St,Suite 412, Los Angeles, CA 90033 USA

[2] Hoag Mem Hosp, Sarcoma Program, Newport Beach, CA USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2016年 / 113卷 / 03期

关键词：

soft tissue sarcoma; extremity; margins; PROSPECTIVE RANDOMIZED-TRIAL; SURGICALLY-TREATED PATIENTS; RADIATION-THERAPY; POSTOPERATIVE RADIOTHERAPY; LOCAL RECURRENCE; ADJUVANT BRACHYTHERAPY; UNPLANNED EXCISION; PROGNOSTIC-SIGNIFICANCE; SINGLE INSTITUTION; MANAGEMENT;

D O I：

10.1002/jso.24112

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

For extremity soft tissue sarcomas, limb salvage is now standard of care. The extent of surgical margins is balanced with functionality of the resected limb. Although negative margins are the goal, the necessary width is unclear. Additional considerations for margin adequacy include presence of anatomic barriers such as fascia and periosteum, proximity of critical structures, receipt of adjuvant and neoadjuvant therapies, and histologic subtype. Multidisciplinary team discussion is critical for treatment planning. (c) 2015 Wiley Periodicals, Inc.

引用

页码：333 / 338

页数：6

共 71 条

[1] POSITIVE SURGICAL MARGINS IN SOFT TISSUE SARCOMA TREATED WITH PREOPERATIVE RADIATION: IS A POSTOPERATIVE BOOST NECESSARY? [J].

Al Yami, Ali ;

Griffin, Anthony M. ;

Ferguson, Peter C. ;

Catton, Charles N. ;

Chung, Peter W. M. ;

Bell, Robert S. ;

Wunder, Jay S. ;

O'Sullivan, Brian .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 77 (04) :1191-1197

[2] Adjuvant radiotherapy for margin-positive high-grade soft tissue sarcoma of the extremity [J].

Alektiar, KM ;

Velasco, J ;

Zelefsky, MJ ;

Woodruff, JM ;

Lewis, JJ ;

Brennan, MF .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2000, 48 (04) :1051-1058

[3] Adjuvant brachytherapy for primary high-grade soft tissue sarcoma of the extremity [J].

Alektiar, KM ;

Leung, D ;

Zelefsky, MJ ;

Healey, JH ;

Brennan, MF .

ANNALS OF SURGICAL ONCOLOGY, 2002, 9 (01) :48-56

[4]

[Anonymous], 1999, Virchows Arch, V434, P187

[5]

[Anonymous], 1985, JAMA, V254, P1791

[6]

[Anonymous], GREENFIELDS SURG SCI

[7] The role of radiation therapy in the management of dermatofibrosarcoma protuberans [J].

Ballo, MT ;

Zagars, GK ;

Pisters, P ;

Pollack, A .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 40 (04) :823-827

[8] Monitoring the Adequacy of Surgical Margins After Resection of Bone and Soft-Tissue Sarcoma [J].

Biau, David J. ;

Weiss, Kurt R. ;

Bhumbra, Rej S. ;

Davidson, Darin ;

Brown, Chris ;

Griffin, Anthony ;

Wunder, Jay S. ;

Ferguson, Peter C. .

ANNALS OF SURGICAL ONCOLOGY, 2013, 20 (06) :1858-1864

[9]

Bichakjian CK, 2015, NATL COMPREHESIVE CA

[10] What is new in the local approach of limb sarcomas and desmoid tumours? [J].

Bonvalot, S. ;

Rimareix, F. ;

Paumier, A. ;

Roberti, E. ;

Bouzaiene, H. ;

Le Pechoux, C. .

CANCER RADIOTHERAPIE, 2010, 14 (6-7) :455-459

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