Photodegradation kinetic study and stability-indicating assay of danazol using high-performance liquid chromatography

被引：0
作者：
Kariem, EAG [1 ]
Abounassif, MA [1 ]
Hagga, ME [1 ]
Al-Khamees, HA [1 ]
机构：
[1] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2000年 / 23卷 / 2-3期
关键词：
danazol; HPLC; UV irradiation; determination; photodegradation; kinetics;
D O I：
暂无
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A selective high-performance liquid chromatographic procedure for the stability-indicating determination of danazol in the presence of its photolytic degradation products is demonstrated. The photolysis was carried out in glass vials and quartz cell under UV light at 254 nm. Satisfactory results were obtained for the assay and recovery testing with RSD values less than 2%. Kinetic parameters evaluated comprise the order of reaction and the rate constants of the degradation of the danazol irradiated in glass vials or quartz cell. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：413 / 420
页数：8
相关论文
共 50 条
[21]   Development of a stability indicating high-performance liquid chromatography method for determination of cenobamate: study of basic degradation kinetics [J].
EL-Malla, Samah F. ;
Mansour, Fotouh R. ;
Elbastawissy, Almoataz Bellah B. ;
Elagamy, Samar H. .
BMC CHEMISTRY, 2024, 18 (01)
[22]   STABILITY OF FAMOTIDINE IN POLYPROPYLENE SYRINGES USING A STABILITY-INDICATING HPLC ASSAY [J].
Kaushal, Gagan ;
Woldemariam, Million ;
Sayre, Brian E. ;
Prettyman, Terrence .
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2011, 34 (14) :1283-1294
[23]   UV-Derivative Spectrophotometric and Stability-Indicating High-Performance Liquid Chromatographic Methods for Determination of Simvastatin in Tablets [J].
Gomes, Fabio P. ;
Garcia, Pedro L. ;
Alves, Joao M. P. ;
Singh, Anil K. ;
Kedor-Hackmann, Erika R. M. ;
Santoro, Maria I. R. M. .
LATIN AMERICAN JOURNAL OF PHARMACY, 2009, 28 (02) :261-269
[24]   A Stability Indicating Method for Determination of Odevixibat using High Performance Liquid Chromatography Method [J].
Ahmed, Ahmed M. ;
Nassar, Mohamed W. I. ;
El-Olemy, Ahmed ;
Emara, Mohamed S. .
EGYPTIAN JOURNAL OF CHEMISTRY, 2022, 65 (10) :203-208
[25]   Development and validation of a high-performance liquid chromatographic stability-indicating method for the analysis of Synercid® in quality control, stability and compatibility studies [J].
Vasselle, B ;
Gousset, G ;
Bounine, JP .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1999, 19 (05) :641-657
[26]   Development and validation of a stability-indicating high performance liquid chromatographic assay for determination of cariprazine in bulk form and in drug product [J].
Toujani, E. ;
Mejri, W. ;
Lassoued, H. E. ;
Toujani, S. ;
Fliss, O. ;
Cheikh, M. H. B. ;
Safta, F. .
ANNALES PHARMACEUTIQUES FRANCAISES, 2023, 81 (01) :83-93
[27]   A SENSITIVE ASSAY OF LYSOGANGLIOSIDES USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
KOBAYASHI, T ;
GOTO, I .
BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1081 (02) :159-166
[28]   Development and validation of stability-indicating high performance liquid chromatography method to analyze gatifloxacin in bulk drug and pharmaceutical preparations [J].
Aljuffali, Ibrahim A. ;
Kalam, Mohd. Abul ;
Sultana, Yasmin ;
Imran, Ahamad ;
Alshamsan, Aws .
SAUDI PHARMACEUTICAL JOURNAL, 2015, 23 (01) :85-94
[29]   A stability-indicating reversed-phase high performance liquid chromatography method for simultaneous assay of two corticosteroids and estimation of their related compounds in a pharmaceutical injectable formulation [J].
Lu, Jun ;
Wei, Yuchien ;
Rustum, Abu M. .
JOURNAL OF CHROMATOGRAPHY A, 2010, 1217 (44) :6932-6941
[30]   Development and Validation of Stability-Indicating High-Performance Thin-Layer Chromatography Method for Estimation of Repaglinide in Bulk and in Pharmaceutical Formulation [J].
Jain, P. S. ;
Patel, M. K. ;
Surana, S. J. .
ACTA CHROMATOGRAPHICA, 2013, 25 (03) :531-544
12345